School of Public Health, Department of Biostatistics, Robert C. Byrd Health Sciences Center, West Virginia University, PO Box 9190, Morgantown, WV 26506-9190, USA.
Bone. 2013 Mar;53(1):103-11. doi: 10.1016/j.bone.2012.11.031. Epub 2012 Dec 4.
Use the meta-analytic approach to examine the effects of ground and/or joint reaction force exercise on femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) in men.
Randomized controlled exercise trials ≥ 24 weeks were included. Standardized effect sizes (g) were calculated and pooled using random-effects models, z-score alpha values and 95% confidence intervals (CI). Heterogeneity was examined using Q and I(2). Statistical significance was set at a two-tailed alpha value (p) of ≤ 0.05 and a trend at >0.05 to ≤ 0.10.
A moderate and statistically significant improvement was found at the FN (3 g's, 187 participants, g=0.583, 95% CI=0.031, 1.135, p=0.04, Q=5.6, p=0.06, I(2)=64%) while a small trend was observed at the LS (5 g's, 275 participants, g=0.190, 95% CI=-0.036, 0.416, p=0.10, Q=3.0, p=0.55, I(2)=0%). Results were sensitive to influence analysis as well as collapsing multiple groups from the same studies so that only one g represented each study.
There is currently insufficient evidence to recommend ground and/or joint reaction force exercise for improving and/or maintaining FN and LS BMD in men. Additional well-designed randomized controlled trials are needed before any final recommendations can be formulated.
使用荟萃分析方法研究地面和/或关节反力运动对男性股骨颈（FN）和腰椎（LS）骨密度（BMD）的影响。
纳入了持续时间≥24 周的随机对照运动试验。使用随机效应模型计算并合并标准化效应量（g），采用 z 分数 alpha 值和 95%置信区间（CI）。使用 Q 和 I(2)检验异质性。统计显著性设定为双侧 alpha 值（p）≤0.05，趋势为>0.05 至≤0.10。
FN 处有中度且具有统计学意义的改善（3g，187 名参与者，g=0.583，95%CI=0.031，1.135，p=0.04，Q=5.6，p=0.06，I(2)=64%），而 LS 处仅观察到较小的趋势（5g，275 名参与者，g=0.190，95%CI=-0.036，0.416，p=0.10，Q=3.0，p=0.55，I(2)=0%）。结果对影响分析和将来自同一研究的多个组合并为一个 g 以代表每个研究均敏感。
目前尚无足够证据推荐地面和/或关节反力运动用于改善和/或维持男性 FN 和 LS BMD。需要进行更多设计良好的随机对照试验，然后才能提出任何最终建议。
