Porto-Ferreira Francisco Augusto, de Almeida-Neto Cesar, Murphy Edward L, Montebello Sandra de Camargo, Nogueira Fátima Aparecida Hangai, Koga da Silva Edina Mariko, MacFarland William, Custer Brian
Fundação Pró-Sangue Hemocentro de São Paulo.
Department of Medical Science, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Transfusion. 2017 Jan;57(1):102-107. doi: 10.1111/trf.13882. Epub 2016 Oct 23.
Low return rates for notification and counseling among donors with reactive serologic screening tests have been reported worldwide. A randomized trial to test the effectiveness of text message, letter, or telephone call reminders to improve return among nonresponding first-time blood donors with reactive serologic tests was conducted.
Donors with serologically reactive screening test results who had a cell phone and resided in the metropolitan telephone area code of São Paulo in the period from August 2013 through July 2014 were eligible. A consecutive sample of first-time donors with reactive screening tests who had not responded to a standard letter requesting the donor return to the blood center were randomly assigned to receive a text, a new letter, or a telephone call requesting return for notification and counseling. Return rates were measured over the subsequent 30 days.
The return rate after a phone call reminder was better than that for a text message (39.8% vs. 28.4%; odds ratio [OR], 1.66; 95% confidence interval [CI], 1.05-2.64) but not better than that for a letter (39.8% vs. 34.4%; OR, 1.26; 95% CI, 0.80-1.99). Older age was a predictor of higher rate of return with each year increase in age associated with a 2% increase in the odds of return (OR, 1.02; 95% CI, 1.01-1.04).
In nonresponding serologic reactive donors, telephone call led to a higher return rate than text message. The results of this study suggest that use of text messages, while attractive for its simplicity, will not lead to increased donor notification success after serologically reactive marker results from blood donation in Brazil.
全球范围内均有报道称，血清学筛查试验呈反应性的献血者中，通知和咨询的回访率较低。开展了一项随机试验，以测试短信、信件或电话提醒对提高首次血清学检测呈反应性但未做出回应的献血者回访率的有效性。
2013年8月至2014年7月期间，居住在圣保罗市大都会电话区号范围内、拥有手机且血清学筛查试验结果呈反应性的献血者符合条件。对首次筛查试验呈反应性但未回复要求其返回血液中心的标准信件的献血者进行连续抽样，将其随机分配，分别接收要求返回进行通知和咨询的短信、新信件或电话。在随后的30天内测量回访率。
电话提醒后的回访率高于短信提醒（39.8%对28.4%；优势比[OR]，1.66；95%置信区间[CI]，1.05 - 2.64），但不高于信件提醒（39.8%对34.4%；OR，1.26；95% CI，0.80 - 1.99）。年龄越大，回访率越高，年龄每增加一岁，回访几率增加2%（OR，1.02；95% CI，1.01 - 1.04）。
在血清学检测呈反应性但未做出回应的献血者中，电话提醒的回访率高于短信提醒。本研究结果表明，短信虽因简单而具有吸引力，但在巴西，献血血清学反应性标志物检测结果出来后，使用短信并不能提高对献血者的通知成功率。
