Verma Vivek, Moreno Amy C, Lin Steven H
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
J Clin Med. 2016 Oct 21;5(10):91. doi: 10.3390/jcm5100091.
Radiation therapy (RT) as part of multidisciplinary oncologic care has been marked by profound advancements over the past decades. As part of multimodality therapy for esophageal cancer (EC), a prime goal of RT is to minimize not only treatment toxicities, but also postoperative complications and hospitalizations. Herein, discussion commences with the historical approaches to treating EC, including seminal trials supporting multimodality therapy. Subsequently, the impact of RT techniques, including three-dimensional conformal RT, intensity-modulated RT, and proton beam therapy, is examined through available data. We further discuss existing data and the potential for further development in the future, with an appraisal of the future outlook of technological advancements of RT for EC.
在过去几十年中,作为多学科肿瘤治疗的一部分,放射治疗(RT)取得了显著进展。作为食管癌(EC)多模态治疗的一部分,RT的一个主要目标不仅是将治疗毒性降至最低,还要将术后并发症和住院率降至最低。本文首先讨论了治疗EC的历史方法,包括支持多模态治疗的开创性试验。随后,通过现有数据研究了RT技术的影响,包括三维适形RT、调强RT和质子束治疗。我们进一步讨论了现有数据以及未来进一步发展的潜力,并对EC的RT技术进步的未来前景进行了评估。