Triantafyllou Konstantinos, Gkolfakis Paraskevas, Viazis Nikos, Tsibouris Panagiotis, Tsigaridas Athanasios, Apostolopoulos Periklis, Anastasiou John, Hounda Eleni, Skianis Ioannis, Katopodi Konstantina, Ndini Xhoela, Alexandrakis George, Karamanolis Demetrios G
aHepatogastroenterology Unit, Second Department of Internal Medicine - Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, 'Attikon' University General Hospital bDepartment of Gastroenterology, Evangelismos Hospital cDepartment of Gastroenterology, NIMTS Hospital, Athens, Greece.
Eur J Gastroenterol Hepatol. 2017 Feb;29(2):185-191. doi: 10.1097/MEG.0000000000000771.
Since its introduction, small bowel video capsule endoscopy (VCE) use has evolved considerably.
Evaluation of the temporal changes of small bowel VCE utilization in three tertiary centers in Greece in Era 1 (2002-2009) and Era 2 (2010-2014) and the development a forecast model for future VCE use during 2015-2017.
Data from all small bowel VCE examinations were retrieved and analyzed in terms of the annual number of the performed examinations, their indications and the significance of their findings.
Overall, we evaluated 3724 VCE examinations. The number of studies peaked in 2009 (n=595) and then decreased to reach 225 in 2014. Overall, more (53.8 vs. 51.4%) patients with iron-deficiency anemia and obscure gastrointestinal bleeding (IDA/OGIB) and fewer (10.7 vs. 14%) patients with chronic diarrhea were evaluated in Era 2 compared with Era 1 (P=0.046). In Era 2, there were more nondiagnostic examinations (39.5 vs. 29.3%, P<0.001), whereas the rate of cases with relevant findings decreased from 47.8 to 40.9%. According to the time trend analysis, we developed a forecast model with two scenarios: the pessimistic and the optimistic. Validation of the model with 2015 data showed that reality was close to the pessimistic scenario: the number of exams further decreased to 190, studies carried out for IDA/OGIB increased to 67%, and there were more negative than positive exams (40.7 vs. 39.2%).
The number of VCE studies carried out after the emergence of the financial crisis decreased significantly and VCE indications were optimized. Our forecast model predicts lower numbers of VCE studies, with IDA/OGIB being the dominant indication. However, the predicted increase of negative exams requires further evaluation.
自小肠视频胶囊内镜检查(VCE)问世以来,其应用有了显著发展。
评估希腊三个三级中心在第1阶段(2002 - 2009年)和第2阶段(2010 - 2014年)小肠VCE使用情况的时间变化,并建立一个预测模型以预测2015 - 2017年VCE的未来使用情况。
检索并分析了所有小肠VCE检查的数据,内容包括每年进行检查的数量、检查指征及其结果的意义。
总体而言,我们评估了3724例VCE检查。检查数量在2009年达到峰值(n = 595),然后在2014年降至225例。总体而言,与第1阶段相比,第2阶段评估的缺铁性贫血和不明原因胃肠道出血(IDA/OGIB)患者更多(53.8%对51.4%),慢性腹泻患者更少(10.7%对14%)(P = 0.046)。在第2阶段,非诊断性检查更多(39.5%对29.3%,P < 0.001),而有相关发现的病例比例从47.8%降至40.9%。根据时间趋势分析,我们建立了一个有两种情景的预测模型:悲观情景和乐观情景。用2015年数据对模型进行验证表明,实际情况接近悲观情景:检查数量进一步降至190例,为IDA/OGIB进行的检查增加到67%,阴性检查比阳性检查更多(40.7%对39.2%)。
金融危机出现后进行的VCE检查数量显著下降,VCE指征得到优化。我们的预测模型预测VCE检查数量会减少,IDA/OGIB为主要指征。然而,预测的阴性检查增加需要进一步评估。