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[冲击波碎石术的实验研究]

[Experimental studies on shock-wave cholelithotripsy].

作者信息

Golder W

出版信息

Helv Chir Acta. 1989 Jun;56(1-2):179-82.

PMID:2777600
Abstract

An experimental device for extracorporeal shock-wave cholelithotripsy has been tested. It is characterized by an electromagnetic acoustic source and focussing of the stones by ultrasound. After in vivo experiments with 45 calculi twelve pigs, seven of them with surgically implanted human gallstones, were treated. Most concrements were only partially disintegrated. A combination with MTBE-litholysis improved the results. The by far most important complication we saw were extensive hemorrhages in the basal segments of both lungs. The quite different anatomy suggests that shock-wave cholelithotripsy in man will not be accompanied by severe lung lesions. Patients suffering from gallbladder stones should be treated in the prone position and in deep inspiration. A maximum of 2,000 shock-waves with an energy of 18 to 20 kV should be administered in one session.

摘要

一种用于体外冲击波碎石术的实验装置已经过测试。其特点是采用电磁声源并通过超声聚焦结石。在用45颗结石对12头猪进行体内实验后,其中7头植入了手术获得的人体胆结石并接受了治疗。大多数结石仅被部分分解。与甲基叔丁基醚溶石术联合使用可改善治疗效果。我们所观察到的迄今为止最重要的并发症是双肺基底段广泛出血。人体截然不同的解剖结构表明,人体冲击波碎石术不会伴有严重的肺部病变。患有胆结石的患者应采取俯卧位并在深吸气时接受治疗。单次治疗应施加最多2000次能量为18至20千伏的冲击波。

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