来自动物相关微生物的生物活性天然产物
Bioactive Natural Products from Animal Associated-Microbes.
作者信息
Tian Yuan, Li Yan-Ling, Zhao Feng-Chun
机构信息
College of Life Science, Taishan Medical University, Taian, Shandong, 271016. China.
College of Life Science, Shandong Agricultural University, Taian, Shandong, 271018. China.
出版信息
Mini Rev Med Chem. 2017;17(17):1588-1601. doi: 10.2174/1389557516666161024144014.
OBJECTIVE
Animal associated-microbes are miroorganisms living inside animal hosts during some parts of their life. In view of the special environment, it is considered that the unique microbes might be the producer of new compounds with diversity biological activities.
CONCLUSION
This review summarizes new findings (mainly described since 2011) concerning the characteristics of various natural products that can be extracted from animal associated-microbes, highlighting that animal related microorganisms represent an underexplored reservoir for the discovery of molecules with unique scaffolds and promising biological activities.
目的
动物相关微生物是在其生命的某些阶段生活在动物宿主体内的微生物。鉴于这种特殊环境，人们认为独特的微生物可能是具有多样生物活性的新化合物的生产者。
结论
本综述总结了（主要自2011年以来描述的）有关可从动物相关微生物中提取的各种天然产物特征的新发现，强调动物相关微生物是一个尚未充分探索的宝库，可用于发现具有独特骨架和有前景生物活性的分子。
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