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潜在的药理学资源:来自海洋真菌的天然生物活性化合物

Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi.

作者信息

Jin Liming, Quan Chunshan, Hou Xiyan, Fan Shengdi

机构信息

College of Life Science, Dalian Nationalities University, No. 18, LiaoHe West Road, Dalian 116600, China.

出版信息

Mar Drugs. 2016 Apr 22;14(4):76. doi: 10.3390/md14040076.

Abstract

In recent years, a considerable number of structurally unique metabolites with biological and pharmacological activities have been isolated from the marine-derived fungi, such as polyketides, alkaloids, peptides, lactones, terpenoids and steroids. Some of these compounds have anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, antibiotic and cytotoxic properties. This review partially summarizes the new bioactive compounds from marine-derived fungi with classification according to the sources of fungi and their biological activities. Those fungi found from 2014 to the present are discussed.

摘要

近年来,从海洋来源的真菌中分离出了大量具有生物和药理活性的结构独特的代谢产物,如聚酮化合物、生物碱、肽、内酯、萜类化合物和甾体化合物。其中一些化合物具有抗癌、抗菌、抗真菌、抗病毒、抗炎、抗氧化、抗生和细胞毒性特性。本综述根据真菌来源及其生物活性对海洋来源真菌中的新生物活性化合物进行了部分总结,并讨论了2014年至今发现的那些真菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b7/4849080/ae0db5d66882/marinedrugs-14-00076-g001.jpg

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