Zhan Da Qin, Chen Xing, Wang Rong, Zhang Jing, Zhao Dan Yu, Zhang Shu Jing, Wang Zhi Feng, Ma Rui Jun, Hou Bo
Department of Internal Medicine, the Affiliated Taihe Hospital of Hubei University, Hubei, China.
Turk J Gastroenterol. 2016 Sep;27(5):444-449. doi: 10.5152/tjg.2016.16215.
BACKGROUND/AIMS: To evaluate the diagnostic significance of appendiceal orifice inflammation (AOI) in ulcerative colitis (UC) patients.
We retrospectively examined data from patients with colitis from May 2010 to January 2014 and assigned them to two groups: UC cases and specific colitis cases. First, we clarified the difference in the AOI+ rate between the two groups. Thereafter, imaging findings of all the patients with colitis were re-examined. Features of AOI alone or in combination with proctitis (referred to as "combination features") were considered as the two separate diagnostic criteria for diagnosing UC. By comparing the current diagnoses with the previous diagnoses, evaluation indexes were obtained.
A total of 3582 colitis cases (UC cases: 427; specific colitis cases: 3155) were examined. The mean AOI+ rates in UC and specific colitis cases were 26.2% and 0.7%, respectively; a Chi-squared test indicated that the difference between these rates was statistically significant (x2=6.81; p<0.001, OR=50.99). When the AOI features alone were used to diagnose UC, the sensitivity was 26.2% [95% confidence interval (CI), 22.3%-30.6%], agreement rate was 90.6%, and specificity was 99.3% (95% CI, 98.9%-99.5%). When the combination features were used to diagnose UC, the sensitivity was 26.2% (95% CI, 22.3%-30.6%), agreement rate was 91.1%, and specificity was 99.9% (95% CI, 99.7%-100%).
Combining AOI features and proctitis may lead to a more effective UC diagnosis and enable physicians to identify this condition more promptly among miscellaneous diseases.
背景/目的：评估阑尾开口炎症（AOI）在溃疡性结肠炎（UC）患者中的诊断意义。
我们回顾性分析了2010年5月至2014年1月期间结肠炎患者的数据，并将他们分为两组：UC病例组和特殊结肠炎病例组。首先，我们明确了两组之间AOI阳性率的差异。此后，对所有结肠炎患者的影像学检查结果进行了重新评估。单独的AOI特征或与直肠炎结合的特征（称为“联合特征”）被视为诊断UC的两个独立诊断标准。通过将当前诊断与先前诊断进行比较，获得评估指标。
共检查了3582例结肠炎病例（UC病例：427例；特殊结肠炎病例：3155例）。UC病例组和特殊结肠炎病例组的平均AOI阳性率分别为26.2%和0.7%；卡方检验表明，这些比率之间的差异具有统计学意义（x2 = 6.81；p < 0.001，OR = 50.99）。当仅使用AOI特征诊断UC时，敏感性为26.2% [95%置信区间（CI），22.3% - 30.6%]，符合率为90.6%，特异性为99.3%（95% CI，98.9% - 99.5%）。当使用联合特征诊断UC时，敏感性为26.2%（95% CI，22.3% - 30.6%），符合率为91.1%，特异性为99.9%（95% CI，99.7% - 100%）。
结合AOI特征和直肠炎可能会导致更有效的UC诊断，并使医生能够在多种疾病中更迅速地识别这种疾病。
