Zhang R C, Qin X, Liu Z H, Tang L Y, Zou Z J, Liang J Y, Wang Y J, Tang Y Q, Lu Y P
Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhonghua Yi Xue Za Zhi. 2016 Oct 18;96(38):3094-3098. doi: 10.3760/cma.j.issn.0376-2491.2016.38.012.
To determine the clinical effect of Friend-Ⅰ External Physical Vibration Lithecbole (EPVL) by Meta-analysis. Pubmed, Embase, Medline, Cochrane Library, Chinese National Knowledge Infrastructure were searched for clinical trials comparing EPVL with the conventional treatment. The quality of included studies was assessed and Meta-analysis was conducted by Review Manager 5.3 software. Five randomized or Quasi-randomized controlled trials met the inclusion criteria. The first day stone expulsion rate of EPVL group was superior to the control group (=4.95, 95% : 3.35-7.32, <0.000 01). Both one-week (=3.13, 95% : 1.95-5.04, <0.000 01) and two-week stone free rate (=4.50, 95% : 2.02-10.00, =0.000 2) were statistically higher in the EPVL group than that in the control group. No severe adverse event occurred during the follow-up. Our study suggested that EPVL could be the effective treatment for upper urinary tract residual stone. However, more high quality randomized controlled trials are needed to better affirm this.
通过Meta分析确定Friend-Ⅰ型体外物理振动排石术（EPVL）的临床效果。检索Pubmed、Embase、Medline、Cochrane图书馆、中国知网中比较EPVL与传统治疗方法的临床试验。评估纳入研究的质量，并使用Review Manager 5.3软件进行Meta分析。五项随机或半随机对照试验符合纳入标准。EPVL组第一天的结石排出率优于对照组（=4.95，95%置信区间：3.35 - 7.32，<0.000 01）。EPVL组的一周结石清除率（=3.13，95%置信区间：1.95 - 5.04，<0.000 01）和两周结石清除率（=4.50，95%置信区间：2.02 - 10.00，=0.000 2）在统计学上均高于对照组。随访期间未发生严重不良事件。我们的研究表明，EPVL可能是治疗上尿路残余结石的有效方法。然而，需要更多高质量的随机对照试验来更好地证实这一点。
