Van Puyvelde L, De Kimpe N, Costa J, Munyjabo V, Nyirankuliza S, Hakizamungu E, Schamp N
Centre Universitaire de Recherche sur la Pharmacopée et la Médecine Traditionnelle, Université Nationale du Rwanda, Butare.
J Nat Prod. 1989 May-Jun;52(3):629-33. doi: 10.1021/np50063a025.
3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of the mp of the latter chalcone, a synthesis of helichrysetin was developed. 3-O-Methylquercetin was shown to be an active principle as it displayed antimicrobial activity.
