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黑接骨木提取物——天然抗氧化剂和抗菌化合物。

Sambucus Nigra Extracts-Natural Antioxidants and Antimicrobial Compounds.

机构信息

Department of Chemistry, Poznań University of Life Sciences, 60-637 Poznan, Poland.

Department of Menegment of Food Quality and Safety, Poznań University of Life Sciences, 60-637 Poznan, Poland.

出版信息

Molecules. 2021 May 14;26(10):2910. doi: 10.3390/molecules26102910.

DOI:10.3390/molecules26102910
PMID:34068909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8156197/
Abstract

Due to the health-promoting properties of elderberry fruits, which result from their rich chemical composition, this raw material is widely used in herbal medicine and the food industry. The aim of the study was to demonstrate the antibacterial activity of the elderberry fruit extracts. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The following phenolic acids were predominant: chlorogenic acid, sinapic acid, and t-cinnamic acid. Their average content was, respectively, 139.09, 72.84, 51.29 mg/g extract. Rutin and quercetin (their average content was 1105.39 and 306.6 mg/g extract, respectively) were the dominant flavonoids. The research showed that the elderberry polyphenol extracts exhibited activity against selected strains of bacteria within the concentration range of 0.5-0.05%. The following bacteria were the most sensitive to the extracts: , , , and . Of the compounds under analysis, apigenin, kaempferol and ferulic, protocatechuic, and p-coumarin acids had the greatest influence on the high antibacterial activity of elderberry extracts. The results of the microbiological and chemical analyses of the composition of the extracts were analyzed statistically to indicate the bioactive compounds of the greatest antimicrobial significance.

摘要

由于接骨木果实丰富的化学成分具有促进健康的特性，这种原材料在草药学和食品工业中得到了广泛应用。本研究的目的是展示接骨木果实提取物的抗菌活性。研究表明，提取物中酚酸和类黄酮的含量决定了其抗菌活性。研究表明，提取物中酚酸和类黄酮的含量决定了其抗菌活性。以下是主要的酚酸：绿原酸、芥子酸和肉桂酸。它们的平均含量分别为 139.09、72.84 和 51.29mg/g 提取物。芦丁和槲皮素（其平均含量分别为 1105.39 和 306.6mg/g 提取物）是主要的类黄酮。研究表明，接骨木多酚提取物在 0.5-0.05%的浓度范围内对所选细菌菌株表现出活性。以下细菌对提取物最敏感： 、 、 、 。在所分析的化合物中，芹菜素、山奈酚和阿魏酸、原儿茶酸和对香豆酸对接骨木提取物的高抗菌活性有最大影响。对提取物组成的微生物学和化学分析结果进行了统计分析，以表明具有最大抗菌意义的生物活性化合物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/4885286f00ad/molecules-26-02910-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/f71e4b5e871b/molecules-26-02910-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/c9c6c7b1c3a9/molecules-26-02910-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/2645cbdb939e/molecules-26-02910-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/4885286f00ad/molecules-26-02910-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/f71e4b5e871b/molecules-26-02910-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/c9c6c7b1c3a9/molecules-26-02910-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/2645cbdb939e/molecules-26-02910-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb1/8156197/4885286f00ad/molecules-26-02910-g004.jpg

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