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动物的精神痛苦与精神痛苦的动物模型。

Psychiatric distress in animals versus animal models of psychiatric distress.

机构信息

Departments of Biological Sciences, Neurology and Neurosurgery, Stanford University, Stanford, California, USA and the Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya.

出版信息

Nat Neurosci. 2016 Oct 26;19(11):1387-1389. doi: 10.1038/nn.4397.

DOI:10.1038/nn.4397
PMID:27786183
Abstract

The realm of human uniqueness steadily shrinks; reflecting this, other primates suffer from states closer to depression or anxiety than 'depressive-like' or 'anxiety-like behavior'. Nonetheless, there remain psychiatric domains unique to humans. Appreciating these continuities and discontinuities must inform the choice of neurobiological approach used in studying any animal model of psychiatric disorders. More fundamentally, the continuities reveal how aspects of psychiatric malaise run deeper than our species' history.

摘要

人类独特性的领域不断缩小;反映这一点的是,其他灵长类动物所患的疾病更接近抑郁或焦虑,而不是“类似抑郁”或“类似焦虑”的行为。尽管如此,仍然存在一些只存在于人类身上的精神疾病领域。在选择用于研究任何精神疾病动物模型的神经生物学方法时,了解这些连续性和不连续性至关重要。更根本的是,这些连续性揭示了精神不适的某些方面比我们物种的历史更为深刻。

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