Lee Yu, Wu Yi-Shan, Chien Chih-Yen, Fang Fu-Min, Hung Chi-Fa
Department of Psychiatry.
Department of Otolaryngology.
Neuropsychiatr Dis Treat. 2016 Oct 13;12:2649-2657. doi: 10.2147/NDT.S112069. eCollection 2016.
The purposes of this study are 1) to estimate the prevalence of common mental disorders including depressive disorder in patients with head and neck cancer (HNC) at baseline and at the 6-month follow-up and 2) to test the validity of two self-reported questionnaires, the Hospital Anxiety and Depression Scale (HADS) and the Taiwanese Depression Questionnaire (TDQ), for screening depression in patients with HNC.
Participants were recruited from the outpatient collaborative care clinic for HNC of a tertiary hospital in Taiwan between January 2010 and January 2011. Ninety-three patients with HNC were enrolled and assessed using the HADS, TDQ, and Structured Clinical Interview for , fourth edition, Patient edition, at baseline and at the 6-month follow-up. Conventional validity indices of the HADS and TDQ were examined.
Our results showed that the validity of the TDQ was satisfactory and comparable to that of both the HADS depression subscale and the HADS total scale. The cutoff scores of the HADS and TDQ for screening possible depressive disorders were 8 and 15, respectively. The areas under the receiver operating characteristic curve of the HADS and TDQ were mean 0.975±0.015 and 0.966±0.019, respectively. Thirteen participants (14%) were diagnosed with depressive disorders at the 6-month follow-up, compared with 8.5% at baseline.
Our results indicate that both the HADS and TDQ are valid instruments for screening depression in patients with HNC.
本研究的目的是:1)估计头颈癌(HNC)患者在基线期和6个月随访时常见精神障碍(包括抑郁症)的患病率;2)检验两种自我报告问卷——医院焦虑抑郁量表(HADS)和台湾抑郁问卷(TDQ)——用于筛查HNC患者抑郁症的有效性。
2010年1月至2011年1月期间,从台湾一家三级医院的HNC门诊协作护理诊所招募参与者。93例HNC患者在基线期和6个月随访时使用HADS、TDQ以及《精神疾病诊断与统计手册》第四版患者版结构化临床访谈进行评估。检查了HADS和TDQ的传统效度指标。
我们的结果显示,TDQ的效度令人满意,与HADS抑郁分量表和HADS总量表相当。HADS和TDQ筛查可能的抑郁症的临界值分别为8分和15分。HADS和TDQ的受试者工作特征曲线下面积分别为0.975±0.015和0.966±0.019。13名参与者(14%)在6个月随访时被诊断为抑郁症,而基线期为8.5%。
我们的结果表明,HADS和TDQ都是筛查HNC患者抑郁症的有效工具。