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原发性肾淋巴瘤——一例报告及文献综述

Primary Renal Lymphoma - A Case Report and Review of Literature.

作者信息

Shetty Shraddha, Singh Avinash Chandra, Babu Vinod

机构信息

Resident, Department of General Surgery, Victoria Hospital, Bangalore Medical College and Research Institute , Bengaluru, Karnataka, India .

出版信息

J Clin Diagn Res. 2016 Sep;10(9):XD05-XD07. doi: 10.7860/JCDR/2016/20901.8577. Epub 2016 Sep 1.

Abstract

Primary Renal Lymphoma (PRL) is rare and its existence has been called into question due to the absence of lymphatic tissue within renal parenchyma. Non-specific abdominal pain with mass in the lumbar region and otherwise unexplained renal failure is the most common presentation. Almost all patients eventually develop extrarenal lymphomatous disease and few patients survive beyond one year. Surgical treatment is rarely feasible as primary modality of treatment since the tumour often encases major vessels and surrounding organs necessitating major resection. Instead, an attempt can be made to downstage the tumour with chemotherapy before attempting surgery. Here we present a case of primary renal Non-Hodgkins Lymphoma (NHL) which was treated with chemotherapy but the patient succumbed to disease before the third cycle.

摘要

原发性肾淋巴瘤(PRL)较为罕见,由于肾实质内缺乏淋巴组织,其存在一直受到质疑。最常见的表现是伴有腰部肿块的非特异性腹痛以及不明原因的肾衰竭。几乎所有患者最终都会发展为肾外淋巴瘤疾病,很少有患者能存活超过一年。由于肿瘤常常包绕大血管和周围器官,需要进行大范围切除,因此手术治疗作为主要治疗方式很少可行。相反,可以在尝试手术前先通过化疗使肿瘤降期。在此,我们报告一例原发性肾非霍奇金淋巴瘤(NHL)病例,该病例接受了化疗,但患者在第三个疗程前死于疾病。

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