Rajkumar S, Iyer R, Culora G, Lane G
Department of Gynaecological Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Department of Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Gynecol Oncol Rep. 2016 Oct 11;18:15-17. doi: 10.1016/j.gore.2016.10.002. eCollection 2016 Nov.
Large cell neuroendocrine cervical carcinoma (LCNEC) is a rare and aggressive cancer that tends to spread and recur early despite intensive multimodal treatment. Conventional treatment strategies for early stage neuroendocrine tumour (NET) include radical hysterectomy followed by adjuvant chemotherapy. There are only 2 reported cases of fertility sparing treatment for NET. We report on the first case of successful conception and delivery at term following radical trachelectomy for early stage LCNEC.
大细胞神经内分泌宫颈癌（LCNEC）是一种罕见且侵袭性强的癌症，尽管进行了强化多模式治疗，仍易于早期扩散和复发。早期神经内分泌肿瘤（NET）的传统治疗策略包括根治性子宫切除术，随后进行辅助化疗。关于NET保留生育功能治疗的报道仅有2例。我们报告了首例早期LCNEC患者在根治性宫颈切除术后成功足月受孕并分娩的病例。
