体外恒牙龋病检测的激光荧光：系统评价和荟萃分析。
Laser fluorescence of caries detection in permanent teeth in vitro: a systematic review and meta-analysis.
机构信息
Universidade do Extremo Sul Catarinense Ringgold standard institution Criciuma, SC, Brazil.
出版信息
J Evid Based Med. 2016 Nov;9(4):213-224. doi: 10.1111/jebm.12227.
BACKGROUND/OBJECTIVES: The detection of dental caries in the early stages, particularly on the occlusal surfaces, has become a mainstay of contemporary clinical practice. The objective of the study was to verify the accuracy of laser fluorescence for caries detection.
METHODS
A comprehensive search of the MEDLINE (PubMed), EMBase, Cochrane Central Register of Controlled Trials, IBECS, BIOSIS, Web of Science, SCOPUS, Congress Abstracts, and Grey literature databases was undertaken from 1980 through January 2016. We included cross-sectional studies that evaluated laser fluorescence in caries diagnoses in vitro and compared them with histological analyses.
RESULTS
A total of 39 articles were included in the meta-analysis, which included 2082 caries sites. The pooled sensitivity was 0.71 (0.69, 0.73), and the specificity was 0.81 (0.73, 0.82). The diagnostic odds ratio was 14.93 (11.2, 19.9). A summary receiver operating characteristic curve was constructed. The area under the curve was 0.865.
CONCLUSION
This meta-analysis showed that laser fluorescence in vitro had the ability to diagnose occlusal caries lesions in permanent teeth and enamel and dentin caries.
背景/目的：在早期阶段检测龋齿，特别是在咬合面上，已成为当代临床实践的主要手段。本研究的目的是验证激光荧光在龋齿检测中的准确性。
方法
从 1980 年到 2016 年 1 月，对 MEDLINE（PubMed）、EMBase、Cochrane 中央对照试验注册中心、IBECS、BIOSIS、Web of Science、SCOPUS、会议摘要和灰色文献数据库进行了全面检索。我们纳入了评估激光荧光在体外龋齿诊断中的横断面研究，并将其与组织学分析进行了比较。
结果
共有 39 篇文章纳入荟萃分析，其中包括 2082 个龋齿部位。汇总敏感性为 0.71（0.69，0.73），特异性为 0.81（0.73，0.82）。诊断比值比为 14.93（11.2，19.9）。构建了汇总受试者工作特征曲线。曲线下面积为 0.865。
结论
本荟萃分析表明，体外激光荧光具有诊断恒牙和釉质及牙本质龋齿的能力。
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