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1
Metabolic cooperation between mouse embryonal carcinoma cells and their differentiated derivatives.小鼠胚胎癌细胞与其分化衍生物之间的代谢合作。
Proc Natl Acad Sci U S A. 1978 Jul;75(7):3292-6. doi: 10.1073/pnas.75.7.3292.
2
Metabolic co-operation in HGPRT+ and HGPRT- embryonal carcinoma cells.次黄嘌呤鸟嘌呤磷酸核糖转移酶阳性（HGPRT+）和次黄嘌呤鸟嘌呤磷酸核糖转移酶阴性（HGPRT-）胚胎癌细胞中的代谢合作
Dev Biol. 1977 Feb;55(2):271-84. doi: 10.1016/0012-1606(77)90172-5.
3
Dominance and independent segregation of metabolic cooperation-competence and pluripotency in an embryonal carcinoma cell hybrid.胚胎癌细胞杂种中代谢合作能力与多能性的显性及独立分离
Exp Cell Res. 1989 Mar;181(1):40-50. doi: 10.1016/0014-4827(89)90180-8.
4
Characterization of a human teratocarcinoma cell assay for inhibitors of metabolic cooperation.用于代谢协同作用抑制剂的人畸胎瘤细胞检测方法的特性分析
Cancer Res. 1986 Mar;46(3):1359-66.
5
Metabolic cooperation in aggregates of embryonal carcinoma cells.
Dev Biol. 1987 May;121(1):288-91. doi: 10.1016/0012-1606(87)90162-x.
6
Murine embryonal carcinoma hybrids: decreased ability to spontaneously differentiate as a dominant trait.小鼠胚胎癌杂种细胞：自发分化能力降低作为一种显性性状。
J Cell Physiol. 1981 Nov;109(2):195-204. doi: 10.1002/jcp.1041090202.
7
Chimeric mice derived from human-mouse hybrid cells.源自人鼠杂交细胞的嵌合小鼠。
Proc Natl Acad Sci U S A. 1978 Apr;75(4):1914-8. doi: 10.1073/pnas.75.4.1914.
8
Isolation of metabolic cooperation-defective variants from mouse embryonal carcinoma cells.
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9
[Influence of cell-cell interaction upon differentiation of murine embryonal carcinoma cells].[细胞间相互作用对小鼠胚胎癌细胞分化的影响]
Zhonghua Zhong Liu Za Zhi. 1987 Jan;9(1):2-5.
10
Two multipotent embryonal carcinoma cell lines irreversibly differentiate in defined media.
Dev Biol. 1983 Jan;95(1):126-36. doi: 10.1016/0012-1606(83)90012-x.

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Gap junctions and cancer: communicating for 50 years.间隙连接与癌症：五十载的交流历程
Nat Rev Cancer. 2016 Dec;16(12):775-788. doi: 10.1038/nrc.2016.105. Epub 2016 Oct 21.
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The rate of spontaneous mutations in human myeloid cells.人类髓系细胞自发突变率。
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A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene.基于 PIG-A 基因的淋巴样和浆细胞肿瘤基因组不稳定性的定量分析。
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4
Serological identification and cellular distribution of three F9 antigen components.三种F9抗原成分的血清学鉴定及细胞分布
J Exp Med. 1980 Dec 1;152(6):1497-505. doi: 10.1084/jem.152.6.1497.
5
Functional analysis of the mouse H-2Kb gene promoter in embryonal carcinoma cells.
Immunogenetics. 1985;21(6):601-11. doi: 10.1007/BF00395884.
6
Differential Hm antigen expression on EC cells and early differentiated derivatives.EC细胞和早期分化衍生物上Hm抗原的差异表达。
EMBO J. 1985 May;4(5):1177-85. doi: 10.1002/j.1460-2075.1985.tb03757.x.
7
Transfected H-2Kb gene as a cause of embryonal carcinoma cell rejection in vivo.转染的H-2Kb基因作为体内胚胎癌细胞排斥反应的一个原因。
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The structure of the gene coding for the mouse cell adhesion molecule uvomorulin.编码小鼠细胞粘附分子埃兹蛋白的基因结构。
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Junctional modulation in mouse embryonal carcinoma cells by Fab fragments of rabbit anti-embryonal carcinoma cell serum.
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3387-91. doi: 10.1073/pnas.76.7.3387.

本文引用的文献

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Metabolic co-operation between biochemically marked mammalian cells in tissue culture.组织培养中生物化学标记的哺乳动物细胞间的代谢协作。
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The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos.利用植入前和植入后小鼠胚胎的睾丸内移植体培育可移植性畸胎癌。
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Neoplastic differentiation: characteristics of cell lines derived from a murine teratocarcinoma.肿瘤分化：源自小鼠畸胎癌的细胞系特征
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Metabolic coupling, ionic coupling and cell contacts.代谢偶联、离子偶联与细胞接触。
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Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture.培养的小鼠卵裂期胚胎和原始性畸胎瘤细胞共有的表面抗原。
Proc Natl Acad Sci U S A. 1973 Oct;70(10):2988-92. doi: 10.1073/pnas.70.10.2988.
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The preimplantation mammalian embryo: characterization of intercellular junctions and their appearance during development.
Dev Biol. 1975 Aug;45(2):231-50. doi: 10.1016/0012-1606(75)90063-9.
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[Mouse teratocarcinoma: differentiation in cultures of a multipotential primitive cell line (author's transl)].[小鼠畸胎癌：多能原始细胞系培养中的分化（作者译）]
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9
Normal genetically mosaic mice produced from malignant teratocarcinoma cells.由恶性畸胎瘤细胞产生的正常基因镶嵌小鼠。
Proc Natl Acad Sci U S A. 1975 Sep;72(9):3585-9. doi: 10.1073/pnas.72.9.3585.
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Specificity of junctional communication between animal cells.动物细胞间连接通讯的特异性。
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小鼠胚胎癌细胞与其分化衍生物之间的代谢合作。

Metabolic cooperation between mouse embryonal carcinoma cells and their differentiated derivatives.

作者信息

Nicolas J F, Jakob H, Jacob F

出版信息

Proc Natl Acad Sci U S A. 1978 Jul;75(7):3292-6. doi: 10.1073/pnas.75.7.3292.

DOI:10.1073/pnas.75.7.3292
PMID:277927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC392761/
Abstract

Metabolic cooperation has been used as an index of intercellular communication between mouse embryonal carcinoma (EC) and other cell types. EC cells do not cooperate with differentiated cells of various properties or origins. In contrast they cooperate with cells of all other EC lines tested, including a human teratocarcinoma line, but with different efficiencies. This might reflect differences either in cell-cell interactions or in the formation of gap junctions. During in vitro differentiation, EC cells appear to remain isolated from differentiated cell types.

摘要

代谢合作已被用作小鼠胚胎癌（EC）细胞与其他细胞类型之间细胞间通讯的指标。EC细胞不与具有各种特性或来源的分化细胞合作。相反，它们与所有其他测试的EC细胞系的细胞合作，包括一个人畸胎瘤细胞系，但效率不同。这可能反映了细胞间相互作用或间隙连接形成方面的差异。在体外分化过程中，EC细胞似乎与分化细胞类型保持隔离。