Herniman Sarah E, Allott Kelly A, Killackey Eóin, Hester Robert, Cotton Sue M
Orygen, The National Centre of Excellence in Youth Mental Health, Australia; Centre for Youth Mental Health, University of Melbourne, Australia; Melbourne School of Psychological Sciences, University of Melbourne, Australia.
Orygen, The National Centre of Excellence in Youth Mental Health, Australia; Centre for Youth Mental Health, University of Melbourne, Australia.
J Affect Disord. 2017 Jan 15;208:223-229. doi: 10.1016/j.jad.2016.08.068. Epub 2016 Oct 15.
Comorbid depression is common in first-episode schizophrenia spectrum (FES) disorders. Both depression and FES are associated with significant deficits in facial and prosody emotion recognition performance. However, it remains unclear whether people with FES and comorbid depression, compared to those without comorbid depression, have overall poorer emotion recognition, or instead, a different pattern of emotion recognition deficits. The aim of this study was to compare facial and prosody emotion recognition performance between those with and without comorbid depression in FES.
This study involved secondary analysis of baseline data from a randomized controlled trial of vocational intervention for young people with first-episode psychosis (N=82; age range: 15-25 years).
Those with comorbid depression (n=24) had more accurate recognition of sadness in faces compared to those without comorbid depression. Severity of depressive symptoms was also associated with more accurate recognition of sadness in faces. Such results did not recur for prosody emotion recognition.
In addition to the cross-sectional design, limitations of this study include the absence of facial and prosodic recognition of neutral emotions.
Findings indicate a mood congruent negative bias in facial emotion recognition in those with comorbid depression and FES, and provide support for cognitive theories of depression that emphasise the role of such biases in the development and maintenance of depression. Longitudinal research is needed to determine whether mood-congruent negative biases are implicated in the development and maintenance of depression in FES, or whether such biases are simply markers of depressed state.
共病性抑郁在首发精神分裂症谱系（FES）障碍中很常见。抑郁和FES均与面部及韵律情感识别表现的显著缺陷有关。然而，与无共病性抑郁的人相比，患有FES和共病性抑郁的人是否整体上情感识别能力更差，或者相反，是否存在不同的情感识别缺陷模式，仍不清楚。本研究的目的是比较FES中有无共病性抑郁者的面部和韵律情感识别表现。
本研究涉及对一项针对首发精神病青年的职业干预随机对照试验的基线数据进行二次分析（N = 82；年龄范围：15 - 25岁）。
与无共病性抑郁的人相比，患有共病性抑郁的人（n = 24）对面部悲伤表情的识别更准确。抑郁症状的严重程度也与对面部悲伤表情的更准确识别有关。韵律情感识别未出现此类结果。
除横断面设计外，本研究的局限性还包括缺乏对中性情绪的面部和韵律识别。
研究结果表明，共病性抑郁和FES患者在面部情感识别中存在情绪一致的负性偏差，并为强调此类偏差在抑郁发生和维持中作用的抑郁认知理论提供了支持。需要进行纵向研究以确定情绪一致的负性偏差是否与FES中抑郁的发生和维持有关，或者此类偏差是否仅仅是抑郁状态的标志。
