Naqos N, Naim A, Jouhadi H, Taleb A, Bouchbika Z, Benchakroune N, Tawfiq N, Sahraoui S, Benider A
Centre Mohammed-VI pour le traitement des cancers, CHU Ibn-Rochd, Casablanca, Maroc.
Centre Mohammed-VI pour le traitement des cancers, CHU Ibn-Rochd, Casablanca, Maroc.
Cancer Radiother. 2016 Dec;20(8):801-804. doi: 10.1016/j.canrad.2016.06.008. Epub 2016 Oct 25.
Mucinous carcinoma of the breast accounts for 1 to 4% of all breast cancer. There are two histological subtypes: mixed mucinous carcinoma, where the ductal carcinoma is associated with the colloid component, and pure mucinous carcinoma, with a favorable prognosis, where the mucus surrounds the tumour tissue and constitutes a mechanical barrier limiting cell invasion and making this form less aggressive. Our study aimed to determine retrospectively the main epidemiological, clinical, biological, and therapeutic features, as well as the prognosis of this rare form of breast carcinoma.
The authors report 32 cases of mucinous carcinoma of the breast diagnosed in Mohammed-VI centre for cancer treatment in Casablanca.
The average tumour size was 4.5cm (0.5-7cm). We found ten positive lymph node dissections, seven of them were of mixed mucinous carcinoma with a tumour size ranging between 4 and 7cm. Mucinous carcinoma was pure in 16 cases, mixed in 14 and a neuroendocrine differentiation was found in two cases. Most tumours were of an intermediate histological grade (n=19) with positive hormonal receptors (68%). After a mean follow-up of 30 months, complete remission was maintained in 92% of evaluable patients.
Mucinous carcinoma is a rare type of breast cancer, with a favourable prognosis for the pure form.
乳腺黏液癌占所有乳腺癌的1%至4%。有两种组织学亚型：混合性黏液癌，其中导管癌与黏液成分相关；纯黏液癌，预后良好，黏液围绕肿瘤组织并构成限制细胞侵袭的机械屏障，使这种类型的侵袭性较小。我们的研究旨在回顾性地确定这种罕见乳腺癌的主要流行病学、临床、生物学和治疗特征以及预后。
作者报告了在卡萨布兰卡穆罕默德六世癌症治疗中心诊断出的32例乳腺黏液癌病例。
肿瘤平均大小为4.5厘米（0.5 - 7厘米）。我们发现10例淋巴结清扫阳性，其中7例为混合性黏液癌，肿瘤大小在4至7厘米之间。黏液癌为纯型的有16例，混合型的有14例，2例发现有神经内分泌分化。大多数肿瘤为中等组织学分级（n = 19），激素受体阳性（68%）。平均随访30个月后，92%的可评估患者维持完全缓解。
黏液癌是一种罕见的乳腺癌类型，纯型预后良好。
