Schürch S, Goerke J, Clements J A
Proc Natl Acad Sci U S A. 1978 Jul;75(7):3417-21. doi: 10.1073/pnas.75.7.3417.
We measured alveolar surface tension directly by observing the spreading properties of fluid droplets placed by micropipette within individual alveoli. Alveolar surface tension in excised rat lungs at total lung capacity and 37 degrees was 29.7 +/- 1.4 mN-m-1. In lungs held at functional residual capacity, surface tension changed slowly, rising to 9 mN-m-1 at 30 min with a subsequent approximately linear rise to 16 mN-m-1 at 115 min. Thereafter it rose more rapidly (20 mN-m-1 at 140 min), suggesting that it was not asymptotically approaching an equilibrium value.
我们通过观察微量移液器置于单个肺泡内的液滴的铺展特性，直接测量了肺泡表面张力。在总肺容量和37摄氏度条件下，切除的大鼠肺的肺泡表面张力为29.7±1.4 mN·m⁻¹。在功能残气量下保持的肺中，表面张力变化缓慢，在30分钟时升至9 mN·m⁻¹，随后在115分钟时以近似线性的方式升至16 mN·m⁻¹。此后上升更快（在140分钟时为20 mN·m⁻¹），这表明它并非渐近地接近平衡值。
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