Schürch S, Bachofen H, Weibel E R
Respir Physiol. 1985 Oct;62(1):31-45. doi: 10.1016/0034-5687(85)90048-9.
In excised, perfused rabbit lungs the alveolar surface tension was measured in individual alveoli over the entire P-V loop at different temperatures (22 and 37 degrees C), using an improved microdroplet method. Additional in vitro experiments are reassuring that the microdroplets do not affect the properties of the alveolar surface film. The in situ measurements show that the alveolar surface tension and the surface tension to volume relation are essentially the same at 22 and 37 degrees C. A maximal surface tension of about 30 mN X m-1 was measured at TLC, and there is a substantial surface tension to volume hysteresis, which amounts to almost 10 mN X m-1 in the middle volume range of a complete pressure volume cycle of the lung. However, with respect to the absolute values of alveolar surface tension, and the shape and width of the hysteresis, these directly obtained results are different from previous findings.
在离体灌注兔肺中，采用改进的微滴法，在不同温度（22和37摄氏度）下，在整个压力-容积环上测量单个肺泡的肺泡表面张力。另外的体外实验证实微滴不会影响肺泡表面膜的特性。原位测量表明，在22和37摄氏度时，肺泡表面张力以及表面张力与容积的关系基本相同。在肺总量（TLC）时测得的最大表面张力约为30 mN·m⁻¹，并且存在显著的表面张力-容积滞后现象，在肺完整压力-容积循环的中间容积范围内，滞后量几乎达到10 mN·m⁻¹。然而，就肺泡表面张力的绝对值以及滞后现象的形状和宽度而言，这些直接获得的结果与先前的发现不同。
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