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[超声检查在绝经后子宫出血探查中的作用]

[The contribution of ultrasonography in the exploration of postmenopausal metrorrhagias].

作者信息

Boudaya Fethia, Jenayah Amel Achour, Saoudi Sarah, Gharsa Anissa, Gharbi Eya, Sfar Ezzeddine, Chelli Dalenda

机构信息

Service de Gynécologie Obstétrique «A», Centre de Maternité et de Néonatologie de Tunis, Tunisie.

出版信息

Pan Afr Med J. 2016 Jun 30;24:175. doi: 10.11604/pamj.2016.24.175.7361. eCollection 2016.

DOI:10.11604/pamj.2016.24.175.7361
PMID:27795772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5072878/
Abstract

Post-menopausal metrorrhagias represent a frequent reason for consultation in gynecology. Our study aims to evaluate the contribution of pelvic ultrasonography in the exploration of endocavitary lesions in people experiencing this symptom and to compare the results found with those of hysteroscopy and histology. This was an analytic retrospective study of 33 cases referred for evaluation of postmenopausal metrorrhagias at the department of gynecology and obstetrics «A» in the Center of Maternity and Neonatology of Tunis in 2012. All patients underwent pelvic ultrasonography and diagnostic hysteroscopy. We analyzed and compare the data obtained with pelvic ultrasonography, hysteroscopy and histological examination. The average age of our patients was 57.78 years and the average age of menopause was 48.36 years. The confrontation between ultrasonographic and histological data showed that ultrasonography has a sensitivity of 80.6%, a specificity of 79.38%, positive predictive value (PPV) of 67.03% and negative predictive value (NPV) of 91.54%. With respect to hysteroscopy these values were 84,44%, 82,72%, 69,93% and 92,65% respectively. Performance level for each exploratory diagnostic tool varied according to the lesion which caused metrorrhagias and generally hysteroscopy was more reliable in the exploration of metrorrhagias than ultrasonography: Youden index 0.67 against 0.59. Our results confirmed data published in the literature that assigns to hysteroscopy a greater reliability compared to pelvic ultrasonography in the diagnosis of endocavitary lesions causing postmenopausal metrorrhagias.

摘要

绝经后子宫出血是妇科门诊常见的就诊原因。我们的研究旨在评估盆腔超声检查在探索出现该症状患者的宫腔内病变中的作用,并将所得结果与宫腔镜检查和组织学检查结果进行比较。这是一项回顾性分析研究,对2012年突尼斯母婴中心妇产科“A”转诊来评估绝经后子宫出血的33例病例进行研究。所有患者均接受了盆腔超声检查和诊断性宫腔镜检查。我们分析并比较了盆腔超声检查、宫腔镜检查和组织学检查所获得的数据。我们患者的平均年龄为57.78岁,平均绝经年龄为48.36岁。超声检查数据与组织学数据对比显示,超声检查的敏感性为80.6%,特异性为79.38%,阳性预测值(PPV)为67.03%,阴性预测值(NPV)为91.54%。与宫腔镜检查相比,这些值分别为84.44%、82.72%、69.93%和92.65%。每种诊断性检查工具的性能水平因引起子宫出血的病变而异,一般来说,宫腔镜检查在子宫出血的探查中比超声检查更可靠:约登指数分别为0.67和0.59。我们的结果证实了文献中发表的数据,即在诊断导致绝经后子宫出血的宫腔内病变方面,与盆腔超声检查相比,宫腔镜检查具有更高的可靠性。

相似文献

1
[The contribution of ultrasonography in the exploration of postmenopausal metrorrhagias].[超声检查在绝经后子宫出血探查中的作用]
Pan Afr Med J. 2016 Jun 30;24:175. doi: 10.11604/pamj.2016.24.175.7361. eCollection 2016.
2
Transvaginal ultrasonography and hysteroscopy as predictors of endometrial polyps in postmenopause.经阴道超声检查和宫腔镜检查作为绝经后子宫内膜息肉的预测指标。
Womens Health (Lond). 2015 Jan;11(1):29-33. doi: 10.2217/whe.14.50.
3
[Comparison of ultrasonographic and hysteroscopic results in perimenopausal metrorrhagias].围绝经期子宫出血的超声检查与宫腔镜检查结果比较
Tunis Med. 2001 Apr;79(4):238-41.
4
[Ultrasonographic hysteroscopy--new approach for the investigation of the uterine cavity in women with postmenopausal bleeding].[超声宫腔镜检查——绝经后出血女性子宫腔检查的新方法]
Akush Ginekol (Sofiia). 1999;38(1):36-8.
5
[Which initial tests should be performed to evaluate meno-metrorrhagias? A comparison of hysterography, transvaginal sonohysterography and hysteroscopy].[应进行哪些初始检查来评估月经过多伴子宫出血?子宫造影、经阴道超声子宫造影和宫腔镜检查的比较]
J Gynecol Obstet Biol Reprod (Paris). 2001 Feb;30(1):59-64.
6
[Abnormal uterine bleeding during climacteric. Correlation between transvaginal ultrasonography, hysteroscopy and histology].[更年期异常子宫出血。经阴道超声检查、宫腔镜检查与组织学之间的相关性]
Minerva Ginecol. 1999 Apr;51(4):125-7.
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Comparison of diagnostic accuracy of saline infusion sonohysterography, transvaginal sonography and hysteroscopy in postmenopausal bleeding.经阴道超声检查、生理盐水灌注子宫声学造影与宫腔镜检查在绝经后出血中的诊断准确性比较。
Arch Gynecol Obstet. 2011 Jul;284(1):111-7. doi: 10.1007/s00404-010-1604-0. Epub 2010 Jul 28.
8
[Postmenopausal bleeding. Comparison between ultrasonography, hysteroscopy and histology results].[绝经后出血。超声检查、宫腔镜检查与组织学结果的比较]
Tunis Med. 2013 Feb;91(2):99-103.
9
Role of hysteroscopy in the detection of endometrial pathologies in women presenting with postmenopausal bleeding and thickened endometrium.宫腔镜在绝经后出血和子宫内膜增厚患者中检测子宫内膜病变中的作用。
Arch Gynecol Obstet. 2012 Mar;285(3):839-43. doi: 10.1007/s00404-011-2068-6. Epub 2011 Aug 26.
10
Detection of benign intracavitary lesions in postmenopausal women with abnormal uterine bleeding: a prospective comparative study on outpatient hysteroscopy and blind biopsy.绝经后异常子宫出血妇女良性腔内病变的检测:门诊宫腔镜检查与盲目活检的前瞻性比较研究
J Minim Invasive Gynecol. 2008 Jan-Feb;15(1):87-91. doi: 10.1016/j.jmig.2007.10.014.

本文引用的文献

1
A systematic review of transvaginal ultrasonography, sonohysterography and hysteroscopy for the investigation of abnormal uterine bleeding in premenopausal women.经阴道超声检查、子宫声学造影和宫腔镜检查用于调查绝经前妇女异常子宫出血的系统评价。
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Tamoxifen, screening and new oestrogen receptor modulators.他莫昔芬、筛查及新型雌激素受体调节剂
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Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities.经阴道超声检查以排除子宫内膜癌及其他子宫内膜异常情况。
JAMA. 1998 Nov 4;280(17):1510-7. doi: 10.1001/jama.280.17.1510.
4
Triage of abnormal postmenopausal bleeding: a comparison of endometrial biopsy and transvaginal sonohysterography versus fractional curettage with hysteroscopy.绝经后异常子宫出血的分诊:子宫内膜活检及经阴道超声子宫造影与宫腔镜下分段刮宫的比较
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5
The role of transvaginal sonography and endometrial biopsy in the evaluation of peri- and postmenopausal bleeding.经阴道超声检查及子宫内膜活检在围绝经期和绝经后出血评估中的作用。
AJR Am J Roentgenol. 1997 Jul;169(1):145-9. doi: 10.2214/ajr.169.1.9207515.
6
Endometrial sonographic and histologic findings in women with and without hormonal replacement therapy suffering from postmenopausal bleeding.接受和未接受激素替代疗法的绝经后出血女性的子宫内膜超声和组织学检查结果
Maturitas. 1997 May;27(1):35-40. doi: 10.1016/s0378-5122(97)01107-9.
7
Office hysteroscopy versus transvaginal ultrasonography in the evaluation of patients with excessive uterine bleeding.宫腔镜检查与经阴道超声检查在评估子宫出血过多患者中的应用比较
Am J Obstet Gynecol. 1996 Jun;174(6):1678-82. doi: 10.1016/s0002-9378(96)70196-5.
8
How should we investigate women with postmenopausal bleeding?我们应该如何对绝经后出血的女性进行调查?
Acta Obstet Gynecol Scand. 1996 May;75(5):475-9. doi: 10.3109/00016349609033357.
9
Hysteroscopy in women with abnormal uterine bleeding on hormone replacement therapy: a comparison with postmenopausal bleeding.激素替代治疗中子宫异常出血女性的宫腔镜检查:与绝经后出血的比较
Fertil Steril. 1996 Jun;65(6):1145-50. doi: 10.1016/s0015-0282(16)58329-0.
10
The sensitivity and specificity of vaginal sonography in detecting endometrial abnormalities in women with postmenopausal bleeding.阴道超声检查对绝经后出血女性子宫内膜异常的敏感性和特异性。
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