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认知状态对股骨颈骨折半髋关节置换术后结局及步行能力的影响:一项前瞻性队列研究

The influence of cognitive status on outcome and walking ability after hemiarthroplasty for femoral neck fracture: a prospective cohort study.

作者信息

Mukka Sebastian, Knutsson Björn, Krupic Ferid, Sayed-Noor Arkan S

机构信息

Department of Surgical and Perioperative Science, Umeå University, 901 87, Umeå, Sweden.

Department of Orthopaedics, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.

出版信息

Eur J Orthop Surg Traumatol. 2017 Jul;27(5):653-658. doi: 10.1007/s00590-016-1873-9. Epub 2016 Oct 31.

Abstract

INTRODUCTION

Femoral neck fracture (FNF) is a devastating injury with serious medical and social consequences. One-third of these patients have some degree of impaired cognitive status. Despite this, a high proportion of hip fracture trials exclude patients with cognitive impairment (CI). We aimed to evaluate whether moderate to severe CI could predict walking ability, quality of life, functional outcome, reoperations and mortality in elderly patients with displaced FNF treated with hemiarthroplasty (HA).

METHODS

This cohort study included a consecutive series of 188 patients treated with HA for a displaced FNF. Patients were assessed for estimated preoperative and 1 year postoperatively with regard to walking ability, cognitive status, quality of life with EQ-5D and hip function with Harris hip score.

RESULTS

There were 188 patients who met the inclusion criteria. A total of 130 patients were in the control group, and 58 were in the CI group. At 1-year follow-up, 31 patients (24%) had died in the control group and 22 patients (38%) had died in the cognitive impaired group. This difference in reoperation and mortality rate was statistically significant (log-rank test, p = 0.016). The CI had a significantly higher incidence of being non-walker (28 vs. 4%, OR 9.2, p = 0.001). The EQ-5D was higher in the control group, while the Harris hip score was comparable in the two groups.

CONCLUSIONS

Moderate to severe CI was associated with a high incidence of non-walking ability, worse quality of life, high mortality and re-operation rate after femoral neck fractures treated with HA.

摘要

引言

股骨颈骨折(FNF)是一种具有严重医学和社会后果的灾难性损伤。这些患者中有三分之一存在一定程度的认知状态受损。尽管如此,仍有很大比例的髋部骨折试验将认知障碍(CI)患者排除在外。我们旨在评估中度至重度CI是否可预测接受半髋关节置换术(HA)治疗的老年移位型FNF患者的行走能力、生活质量、功能结局、再次手术情况和死亡率。

方法

这项队列研究纳入了连续188例接受HA治疗移位型FNF的患者。在术前和术后1年对患者进行评估,内容包括行走能力、认知状态、使用EQ-5D评估的生活质量以及使用Harris髋关节评分评估的髋关节功能。

结果

共有188例患者符合纳入标准。其中130例患者为对照组,58例为CI组。在1年随访时,对照组有31例患者(24%)死亡,认知障碍组有22例患者(38%)死亡。再次手术率和死亡率的这种差异具有统计学意义(对数秩检验,p = 0.016)。CI组非步行者的发生率显著更高(28%对4%,OR 9.2,p = 0.001)。对照组的EQ-5D更高,而两组的Harris髋关节评分相当。

结论

中度至重度CI与接受HA治疗的股骨颈骨折后非行走能力发生率高、生活质量差、高死亡率和再次手术率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1055/5486608/142dcdfc68e6/590_2016_1873_Fig1_HTML.jpg

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