Botou Anna, Bangeas Athanasios, Alexiou Ioannis, Sakkas Lazaros I
Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41 110, Larissa, Greece.
Clin Rheumatol. 2017 Jan;36(1):9-14. doi: 10.1007/s10067-016-3459-7. Epub 2016 Oct 29.
Acro-osteolysis is an osteolysis of the distal phalanges of the hands and feet and can affect the terminal tuft or the shaft of the distal phalanx (transverse or band acro-osteolysis). It is often associated with distal digital ischemia, digital calcinosis, or severe sensory neuropathy. Acro-osteolysis has been associated with a heterogeneous group of disorders, including occupational activities, infections, rheumatic disorders (systemic sclerosis, psoriatic arthritis), endocrinopathies, genetic disorders, and lysosomal storage disorders. Plain radiography is the gold standard for the detection of acro-osteolysis.
肢端骨质溶解是手足远端指骨的骨质溶解，可影响远端指骨的末端指节或骨干（横向或带状肢端骨质溶解）。它常与远端手指缺血、指骨钙化或严重感觉神经病变相关。肢端骨质溶解与一组异质性疾病有关，包括职业活动、感染、风湿性疾病（系统性硬化症、银屑病关节炎）、内分泌病、遗传性疾病和溶酶体贮积症。X线平片是检测肢端骨质溶解的金标准。
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