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Respiratory Syncytial Virus Bronchiolitis: Enter the Microbiome.

作者信息

Gern James E

机构信息

1 School of Medicine and Public Health University of Wisconsin-Madison Madison, Wisconsin.

出版信息

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1044-1045. doi: 10.1164/rccm.201605-1018ED.

DOI:10.1164/rccm.201605-1018ED
PMID:27797613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5440971/
Abstract
摘要

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Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection.呼吸道合胞病毒感染儿童的鼻咽微生物群、宿主转录组与疾病严重程度
Am J Respir Crit Care Med. 2016 Nov 1;194(9):1104-1115. doi: 10.1164/rccm.201602-0220OC.
2
Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria.儿童时期下呼吸道感染的易感性与对致病性气道细菌的细胞因子反应紊乱有关。
Pediatr Infect Dis J. 2016 May;35(5):561-6. doi: 10.1097/INF.0000000000001092.
3
Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial.阿奇霉素治疗 1-3 岁儿童哮喘样症状发作：一项随机、双盲、安慰剂对照试验。
Lancet Respir Med. 2016 Jan;4(1):19-26. doi: 10.1016/S2213-2600(15)00500-7. Epub 2015 Dec 17.
4
The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21.喘息的早期发展。17q21 的环境决定因素和遗传易感性。
Am J Respir Crit Care Med. 2016 Apr 15;193(8):889-97. doi: 10.1164/rccm.201507-1493OC.
5
Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial.阿奇霉素早期给药与预防有严重下呼吸道疾病病史的学龄前儿童发生此类严重疾病：一项随机临床试验
JAMA. 2015 Nov 17;314(19):2034-2044. doi: 10.1001/jama.2015.13896.
6
Minimally Invasive Sampling Method Identifies Differences in Taxonomic Richness of Nasal Microbiomes in Young Infants Associated with Mode of Delivery.微创采样方法揭示了与分娩方式相关的婴儿鼻腔微生物群分类丰富度的差异。
Microb Ecol. 2016 Jan;71(1):233-42. doi: 10.1007/s00248-015-0663-y. Epub 2015 Sep 14.
7
The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.婴儿鼻咽微生物群会影响下呼吸道感染的严重程度和哮喘发生风险。
Cell Host Microbe. 2015 May 13;17(5):704-15. doi: 10.1016/j.chom.2015.03.008. Epub 2015 Apr 9.
8
Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis.临床实践指南：细支气管炎的诊断、管理及预防
Pediatrics. 2014 Nov;134(5):e1474-502. doi: 10.1542/peds.2014-2742.
9
Antibiotics for bronchiolitis in children under two years of age.两岁以下儿童毛细支气管炎的抗生素治疗
Cochrane Database Syst Rev. 2014 Oct 9;2014(10):CD005189. doi: 10.1002/14651858.CD005189.pub4.
10
Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection.呼吸道合胞病毒通过与青霉素结合蛋白1a结合增加肺炎链球菌的毒力。呼吸道感染的一种新范例。
Am J Respir Crit Care Med. 2014 Jul 15;190(2):196-207. doi: 10.1164/rccm.201311-2110OC.