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双侧原发性肾上腺淋巴瘤伴肾上腺功能不全。

Bilateral primary adrenal lymphoma with adrenal insufficiency.

作者信息

Ekhzaimy Aishah, Mujamammi Ahmad

机构信息

Division of Endocrinology, King Saud University, College of Medicine and King Khalid University Hospital, Riyadh, Saudi Arabia.

Clinical Biochemistry, Department of Pathology, King Saud University, College of Medicine, Riyadh, Saudi Arabia.

出版信息

BMJ Case Rep. 2016 Oct 26;2016:bcr2016217417. doi: 10.1136/bcr-2016-217417.

Abstract

Primary adrenal lymphoma is an extremely rare condition. We describe a case of bilateral adrenal lymphoma in a man aged 55 years who was admitted to our hospital. He had a 3-month history of left flank pain, nausea and vomiting with weight loss. A CT scan at a private hospital revealed bilateral large adrenal masses; the patient was referred to our centre based on these findings. He was evaluated for pheochromocytoma by an endocrinology team; however, all findings were negative. In addition, a cosyntropin stimulation test indicated adrenal insufficiency. A Trucut biopsy of the adrenal gland revealed diffuse large B-cell lymphoma of the adrenal glands, and the patient responded extremely well to chemotherapy.

摘要

原发性肾上腺淋巴瘤是一种极其罕见的疾病。我们报告一例55岁男性双侧肾上腺淋巴瘤病例,该患者入住我院。他有3个月的左侧腰痛、恶心、呕吐伴体重减轻病史。一家私立医院的CT扫描显示双侧肾上腺有巨大肿块;基于这些检查结果,患者被转诊至我院。内分泌团队对他进行了嗜铬细胞瘤评估;然而,所有检查结果均为阴性。此外,促肾上腺皮质激素刺激试验表明存在肾上腺功能不全。肾上腺组织芯针活检显示肾上腺弥漫性大B细胞淋巴瘤,该患者对化疗反应非常良好。

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