Iwahara Yoshihito, Shinohara Tsutomu, Naruse Keishi, Komatsu Yukihisa
Division of Hematology, National Hospital Organization Kochi Hospital, Kochi, Japan.
Division of Clinical Investigation, National Hospital Organization Kochi Hospital, Kochi, Japan.
BMJ Case Rep. 2017 Jan 31;2017:bcr2016218222. doi: 10.1136/bcr-2016-218222.
Primary bone lymphoma and primary adrenal lymphoma are rare clinicopathological entities of non-Hodgkin's lymphoma (NHL). We present the first case of diffuse large B-cell lymphoma with the involvement of a single bone and both adrenal glands alone with adrenal insufficiency. As primary extranodal NHL may have other unusual extranodal lesions, which may present unexplained clinical findings, patients with primary extranodal NHL require careful systemic examination, even when lymphadenopathy is absent.
原发性骨淋巴瘤和原发性肾上腺淋巴瘤是非霍奇金淋巴瘤(NHL)中罕见的临床病理实体。我们报告首例仅累及单一骨骼和双侧肾上腺并伴有肾上腺功能不全的弥漫性大B细胞淋巴瘤。由于原发性结外NHL可能有其他不寻常的结外病变,这些病变可能呈现无法解释的临床症状,因此原发性结外NHL患者即使没有淋巴结病,也需要进行仔细的全身检查。