Aschieri D, Astorri E
Minerva Cardioangiol. 1989 May;37(5):215-8.
The aim of this study was to evaluate left ventricular function in 26 patients with essential arterial hypertension, compared with 33 normal subjects, using gated radionuclide ventriculography. The hypertensive patients had reduced values of ventricular ejection fraction (EF), peak ejection and peak filling (PRF) rates. A group of 10 hypertensive patients with normal EF, showed significantly reduced values of PFR, as compared to normal subjects. The older hypertensive patients had significantly reduced PRF values, compared to younger patients. PFR is a more sensitive index in evaluating the impairment of ventricular function in patients with hypertension, though it lacks real discriminating diagnostic value. In hypertrophic heart disease the association between arterial hypertension and old age contributed to accentuate the abnormality in ventricular diastolic filling.
本研究旨在通过门控放射性核素心室造影术，评估26例原发性高血压患者的左心室功能，并与33名正常受试者进行比较。高血压患者的心室射血分数（EF）、射血峰值和充盈峰值（PRF）率均降低。一组10例EF正常的高血压患者，与正常受试者相比，其PFR值显著降低。老年高血压患者的PRF值与年轻患者相比显著降低。尽管PFR缺乏真正的鉴别诊断价值，但它是评估高血压患者心室功能损害的更敏感指标。在肥厚性心脏病中，动脉高血压与老年之间的关联加剧了心室舒张期充盈异常。
