Elgin Ufuk, Şen Emine, Şimşek Tülay, Tekin Kemal, Yılmazbaş Pelin
Ulucanlar Eye Research and Training Hospital, Ophthalmology Clinic, Ankara, Turkey.
Osmangazi University Faculty of Medicine, Department of Ophthalmology, Eskişehir, Turkey.
Turk J Ophthalmol. 2016 Jun;46(3):95-98. doi: 10.4274/tjo.92604. Epub 2016 Jun 6.
To compare the effect of cataract surgery on anterior segment parameters measured by optical biometry in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG).
Twenty-five eyes of 25 patients with POAG and 29 eyes of 29 patients with PXG who had uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery were included to our prospective study. Central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) were measured with an optical biometer preoperatively and at 1 month postoperatively. The pre- and postoperative values of intraocular pressure (IOP) and the anterior segment parameters and the differences between POAG and PXG were compared statistically by paired t, independent t and chi-square tests.
The mean values of preoperative CCT (p=0.042) and ACD (p=0.012) were significantly lower in the PXG than in the POAG group. In the PXG group, IOP decreased (p=0.001) but CCT (p=0.03) and ACD (p=0.001) increased significantly postoperatively; AL did not change significantly. In the POAG group, IOP decreased (p=0.01) and ACD (p=0.004) increased significantly postoperatively, while AL and CCT did not change significantly. There were no significant differences in the pre- to postoperative changes in IOP (p=0.76), AL (p=0.44) and CCT (p=0.52) values between the two groups. However, the postoperative increase in ACD was larger in the PXG group (p=0.03).
Cataract surgery may cause some changes in IOP and anterior segment parameters like ACD and CCT postoperatively in eyes with POAG and PXG, and these changes may differ between eyes with PXG and POAG.
比较白内障手术对原发性开角型青光眼(POAG)和剥脱性青光眼(PXG)患者通过光学生物测量法测量的眼前节参数的影响。
本前瞻性研究纳入了25例POAG患者的25只眼和29例PXG患者的29只眼,这些患者均接受了单纯超声乳化白内障吸除术和后房型人工晶状体植入术。术前及术后1个月使用光学生物测量仪测量中央角膜厚度(CCT)、前房深度(ACD)和眼轴长度(AL)。通过配对t检验、独立t检验和卡方检验对两组患者术前和术后的眼压(IOP)值、眼前节参数以及POAG组和PXG组之间的差异进行统计学比较。
PXG组术前CCT(p = 0.042)和ACD(p = 0.012)的平均值显著低于POAG组。在PXG组中,术后眼压降低(p = 0.001),但CCT(p = 0.03)和ACD(p = 0.001)显著增加;AL无明显变化。在POAG组中,术后眼压降低(p = 0.01),ACD(p = 0.004)显著增加,而AL和CCT无明显变化。两组间眼压(p = 0.76)、AL(p = 0.44)和CCT(p = 0.52)值术前至术后的变化无显著差异。然而,PXG组术后ACD的增加幅度更大(p = 0.03)。
白内障手术可能会使POAG和PXG患者术后眼压及眼前节参数如ACD和CCT发生一些变化,且这些变化在PXG和POAG患者眼中可能有所不同。