Department of Ophthalmology, Waterford Regional Hospital, Waterford, Ireland.
Eye (Lond). 2010 Apr;24(4):519-26; quiz 527. doi: 10.1038/eye.2009.339. Epub 2010 Feb 19.
To study changes in anterior segment morphometry after uneventful phacoemulsification cataract surgery, and to investigate whether there is a relationship between any observed changes and intraocular pressure (IOP) reduction after the procedure.
The anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness (CCT), and IOP were measured in 101 non-glaucomatous eyes before and after uneventful phacoemulsification cataract surgery.
After cataract surgery, the mean ACD, ACV, and ACA values increased by 1.08 mm, 54.4 mm(3), and 13.1 degrees , respectively, and the mean IOP (corrected for CCT) decreased by 3.2 mm Hg. The predictive value of a previously described index (preoperative ACD/preoperative IOP (corrected for CCT) or CPD ratio) for IOP (corrected for CCT) reduction after cataract surgery was confirmed, reflected in an r(2) value of 23.3% between these two parameters (P<0.001). Other indices predictive of IOP reduction after cataract surgery were also identified, including preoperative IOP/preoperative ACV and preoperative IOP/preoperative ACA, reflected in r(2) values of 13.7 and 13.7%, respectively (P<0.001 and P<0.001, respectively).
Our study confirms the predictive value of the CPD ratio for IOP reduction after cataract surgery, and may contribute to the decision-making process in patients with glaucoma or ocular hypertension. Furthermore, two novel indices of preoperative parameters that are predictive for IOP reduction after cataract surgery were identified, and enhance our understanding of the mechanisms underlying IOP changes after this procedure.
研究超声乳化白内障吸除术后眼前节形态学的变化,探讨术后观察到的变化与眼压(IOP)降低之间是否存在关系。
对 101 例非青光眼眼超声乳化白内障吸除术后的前房深度(ACD)、前房容积(ACV)、前房角(ACA)、中央角膜厚度(CCT)和 IOP 进行测量。
白内障手术后,平均 ACD、ACV 和 ACA 值分别增加 1.08mm、54.4mm(3)和 13.1 度,平均 IOP(校正 CCT)降低 3.2mmHg。术前 ACD/术前 IOP(校正 CCT)或 CPD 比值预测白内障术后 IOP(校正 CCT)降低的价值得到了证实,这两个参数之间的 r(2)值为 23.3%(P<0.001)。还确定了其他预测白内障术后 IOP 降低的指数,包括术前 IOP/术前 ACV 和术前 IOP/术前 ACA,r(2)值分别为 13.7%和 13.7%(P<0.001 和 P<0.001)。
本研究证实了 CPD 比值对白内障术后 IOP 降低的预测价值,可能有助于青光眼或高眼压症患者的决策过程。此外,还确定了两个预测白内障术后 IOP 降低的新的术前参数指数,增强了我们对该手术术后眼压变化机制的理解。