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本文引用的文献

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Toxicity and Sorbate Sensitivity of Molds Isolated from Surplus Commodity Cheeses .从剩余商品奶酪中分离出的霉菌的毒性和山梨酸盐敏感性
J Food Prot. 1988 Jun;51(6):457-462. doi: 10.4315/0362-028X-51.6.457.
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Deleterious effects of mycotoxin combinations involving ochratoxin A.涉及赭曲霉毒素 A 的真菌毒素组合的有害影响。
Toxins (Basel). 2013 Nov 1;5(11):1965-87. doi: 10.3390/toxins5111965.
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Natural occurrence, analysis, and prevention of mycotoxins in fruits and their processed products.水果及其加工产品中真菌毒素的自然发生、分析和预防。
Crit Rev Food Sci Nutr. 2014;54(1):64-83. doi: 10.1080/10408398.2011.569860.
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Comparison of growth characteristics and roquefortin C production ofPenicillium roqueforti from blue-veined cheese.青霉属从蓝纹奶酪中生长特性和罗寇毒素 C 生产的比较。
Mycotoxin Res. 2007 Sep;23(3):122-6. doi: 10.1007/BF02951507.
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Production of metabolites from the Penicillium roqueforti complex.罗克福青霉复合体代谢产物的产生。
J Agric Food Chem. 2006 May 17;54(10):3756-63. doi: 10.1021/jf060114f.
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Enzyme immunoassay for mycophenolic acid in milk and cheese.牛奶和奶酪中霉酚酸的酶免疫测定法。
J Agric Food Chem. 2008 Aug 27;56(16):6857-62. doi: 10.1021/jf801063w. Epub 2008 Jul 9.
7
Stress induction of mycotoxin biosynthesis genes by abiotic factors.非生物因子对霉菌毒素生物合成基因的应激诱导
FEMS Microbiol Lett. 2008 Jul;284(2):142-9. doi: 10.1111/j.1574-6968.2008.01182.x. Epub 2008 May 29.
8
The inability of Byssochlamys fulva to produce patulin is related to absence of 6-methylsalicylic acid synthase and isoepoxydon dehydrogenase genes.黄柄曲霉无法产生展青霉素与缺乏6-甲基水杨酸合酶和异环氧脱氧雪腐镰刀菌烯醇脱氢酶基因有关。
Int J Food Microbiol. 2007 Apr 10;115(2):131-9. doi: 10.1016/j.ijfoodmicro.2006.10.016. Epub 2006 Dec 13.
9
Mycotoxins and other secondary metabolites produced in vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom isolated from baled grass silage in Ireland.从爱尔兰打捆青贮牧草中分离出的潘尼青霉(Frisvad)和罗克福特青霉(Thom)在体外产生的霉菌毒素及其他次生代谢产物。
J Agric Food Chem. 2006 Nov 29;54(24):9268-76. doi: 10.1021/jf0621018.
10
DNA-DNA cross-links contribute to the mutagenic potential of the mycotoxin patulin.DNA-DNA交联作用有助于霉菌毒素棒曲霉素的致突变潜力。
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来自[具体来源未明确]的次生代谢产物,戈贡佐拉奶酪生产的起始物。

Secondary Metabolites from , A Starter for the Production of Gorgonzola Cheese.

作者信息

Vallone Lisa, Giardini Alberto, Soncini Gabriella

机构信息

Dipartimento di Scienze Veterinarie per la Salute, la Produzione Animale e la Sicurezza Alimentare, Università di Milano.

Centro Sperimentale del Latte S.r.l. , Zelo Buon Persico (LO), Italy.

出版信息

Ital J Food Saf. 2014 Sep 11;3(3):2118. doi: 10.4081/ijfs.2014.2118. eCollection 2014 Aug 28.

DOI:10.4081/ijfs.2014.2118
PMID:27800360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5076727/
Abstract

The presence of mold in food, although necessary for production, can involve the presence of secondary metabolites, which are sometimes toxic. is a common saprophytic fungus but it is also the essential fungus used in the production of Roquefort cheese and other varieties of blue cheese containing internal mold. The study was conducted on industrial batches of starters used in the production of the Gorgonzola cheese, with the aim to verify the production of secondary metabolites. Nine strains were tested. The presence of roquefortine C, PR toxin and mycophenolic acid was tested first , then on bread-like substrate and lastly in nine cheese samples produced with the same starters and ready to market. , only out of nine produced roquefortine C, four starters showed mycophenolic acid production, while no significant amounts of PR toxin were detected. In the samples grown on bread-like substrate, did not produce secondary metabolites, likewise with each cheese samples tested. To protect consumers' health and safety, the presence of mycotoxins needs to be verified in food which is widely consumed, above all for products protected by the protected denomination of origin (DOP) label ( a certificate guaranteeing the geographic origin of the product), such as Gorgonzola cheese.

摘要

食品中霉菌的存在虽然是生产所必需的,但可能涉及次生代谢产物的存在,这些次生代谢产物有时是有毒的。是一种常见的腐生真菌,但也是用于生产罗克福尔干酪和其他含有内部霉菌的蓝纹奶酪品种的重要真菌。该研究针对用于生产戈贡佐拉奶酪的工业批次发酵剂进行,目的是验证次生代谢产物的产生。测试了九种菌株。首先检测了罗克福汀C、PR毒素和霉酚酸的存在,然后在面包状底物上检测,最后在使用相同发酵剂生产并准备上市的九个奶酪样品中检测。在九个样品中,只有 个产生了罗克福汀C,四个发酵剂显示出霉酚酸的产生,而未检测到大量的PR毒素。在面包状底物上生长的样品中,没有产生次生代谢产物,测试的每个奶酪样品也是如此。为保护消费者的健康和安全,需要在广泛消费的食品中验证霉菌毒素的存在,尤其是对于受原产地保护标签(DOP)(保证产品地理来源的证书)保护的产品,如戈贡佐拉奶酪。