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八旬老人 Stanford A 型急性主动脉夹层手术修复的早期和晚期结果

Early and Late Outcomes of Surgical Repair for Stanford A Acute Aortic Dissection in Octogenarians.

作者信息

Tochii Masato, Takami Yoshiyuki, Hattori Koji, Ishikawa Hiroshi, Ishida Michiko, Higuchi Yoshiro, Takagi Yasushi

机构信息

Department of Cardiovascular Surgery, Fujita Health University.

出版信息

Circ J. 2016 Nov 25;80(12):2468-2472. doi: 10.1253/circj.CJ-16-0918. Epub 2016 Nov 1.

Abstract

BACKGROUND

Because increased age is a strong independent predictor of mortality and morbidity, surgery for octogenarians with Stanford type A aortic dissection (AAD) may be avoided.

METHODS AND RESULTS

From 2005 to 2015, 158 patients underwent surgical repair for AAD via a median sternotomy. We compared 24 (15.2%) octogenarians (83±3 years) with 134 (84.8%) patients aged ≤79 years (62±13 years), based on retrospectively collected clinical data. Octogenarians were predominantly female (79.2% vs. 44.8%, P=0.0033). Ascending aortic replacement was more frequently performed in the octogenarians (95.8% vs. 65.7%, P=0.0015) and total arch replacement in the younger patients (4.2% vs. 26.9%, P=0.0165). There were 14 hospital deaths among the younger patients, none among the octogenarians (0% vs. 10.4%, P=0.1303), and major morbidity rates were comparable. There were 3 late deaths among the octogenarians and 9 deaths among the younger patients. The respective 1-, 3-, and 5-year survival rates were 94.4%, 81.5%, and 81.5% in the octogenarians and 86.9%, 85.6%, and 83.9% in the younger patients, with no significant differences.

CONCLUSIONS

Surgical repair for AAD in octogenarians showed favorable results when compared with a younger patient cohort, with low hospital mortality rate and excellent late outcomes. Therefore, this technique should not be disregarded just because the patient is an octogenarian. (Circ J 2016; 80: 2468-2472).

摘要

背景

由于年龄增长是死亡率和发病率的强有力独立预测因素,对于患有A型主动脉夹层(AAD)的八旬老人,可能会避免进行手术。

方法与结果

2005年至2015年期间,158例患者通过正中胸骨切开术接受了AAD手术修复。我们根据回顾性收集的临床数据,将24例(15.2%)八旬老人(83±3岁)与134例(84.8%)年龄≤79岁(62±13岁)的患者进行了比较。八旬老人以女性为主(79.2%对44.8%,P=0.0033)。八旬老人更常进行升主动脉置换(95.8%对65.7%,P=0.0015),而年轻患者更常进行全弓置换(4.2%对26.9%,P=0.0165)。年轻患者中有14例住院死亡,八旬老人中无住院死亡(0%对10.4%,P=0.1303),且主要发病率相当。八旬老人中有3例晚期死亡,年轻患者中有9例死亡。八旬老人的1年、3年和5年生存率分别为94.4%、81.5%和81.5%,年轻患者分别为86.9%、85.6%和83.9%,差异无统计学意义。

结论

与年轻患者队列相比,八旬老人AAD手术修复显示出良好结果,住院死亡率低且晚期预后良好。因此,不应仅仅因为患者是八旬老人就忽视这项技术。(《循环杂志》2016年;80:2468 - 2472)

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