Department of Cardiovascular Surgery, Higashi Takarazuka Satoh Hospital, Nagao-cho, Takarazuka, Hyogo, Japan.
Department of Cardiovascular Surgery, Higashi Takarazuka Satoh Hospital, Nagao-cho, Takarazuka, Hyogo, Japan.
J Thorac Cardiovasc Surg. 2016 Aug;152(2):439-46. doi: 10.1016/j.jtcvs.2016.03.093. Epub 2016 Apr 14.
The number of older patients with acute aortic dissection type A (AAD [A]) is increasing as the population ages. We evaluated clinical outcomes for octogenarians with AAD (A) treated surgically at our hospital. Whenever possible, we limited the replacement site of the ascending aorta to the supracoronary and hemiarch.
Of 436 patients with AAD (A) seen in our hospital emergency room between April 2001 and August 2015, 90 were octogenarians. Surgery was performed using a simple cardiopulmonary bypass established through the right femoral artery and venous cannulation, and distal anastomosis was performed under deep hypothermic circulatory arrest at 20°C.
Of the 90 octogenarians with AAD (A), 11 required cardiopulmonary resuscitation, 9 of whom died. Four patients with stable hemodynamics refused surgery. Thus, 77 were treated surgically. Of these 77 patients, isolated replacement of the ascending aorta or hemiarch was performed in 73 (94.8%), and total arch replacement in 4 (5.2%). Five patients (6.5%) died within 30 days, and 5 (6.5%) died in the hospital more than 30 days after surgery. Seven (9.1%) had a new stroke, 5 (6.5%) had pneumonia, and 4 (5.2%) had mediastinitis. Forty-four (57.1%) patients were discharged to their homes and 23 (30%) to rehabilitation hospitals. Three patients later required endovascular stent graft repair, which was successful in each case. The overall postoperative survival was 82%, 70%, and 62% at 1, 3, and 5 years, respectively.
Our results suggest that our limited replacement protocol for emergency AAD (A) surgery has early and midterm survival benefits for octogenarians.
随着人口老龄化,急性主动脉夹层 A 型(AAD[A])患者中老年人的数量正在增加。我们评估了在我院接受手术治疗的 80 岁以上 AAD[A]患者的临床结局。只要可能,我们就将升主动脉置换部位限制在冠状动脉上方和半弓。
2001 年 4 月至 2015 年 8 月期间,我院急诊收治了 436 例 AAD[A]患者,其中 90 例为 80 岁以上老年人。手术采用经右股动脉建立的简单体外循环和静脉插管进行,在 20°C 深低温循环停止下行远端吻合。
90 例 80 岁以上 AAD[A]患者中,11 例需要心肺复苏,其中 9 例死亡。4 例血流动力学稳定的患者拒绝手术。因此,77 例患者接受了手术治疗。在这 77 例患者中,73 例(94.8%)行单纯升主动脉或半弓置换,4 例(5.2%)行全主动脉弓置换。术后 30 天内 5 例(6.5%)死亡,术后 30 天以上 5 例(6.5%)死亡。7 例(9.1%)新发脑卒中,5 例(6.5%)肺炎,4 例(5.2%)纵隔炎。44 例(57.1%)患者出院回家,23 例(30%)出院至康复医院。3 例患者随后需要血管内支架修复,均获得成功。术后总体生存率分别为 1 年、3 年和 5 年时的 82%、70%和 62%。
我们的结果表明,我们对急性 AAD[A]手术的有限置换方案为 80 岁以上老年人带来了早期和中期生存获益。