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上海某综合医院成人急性腹泻的病因学特征

Aetiological characteristics of adult acute diarrhoea in a general hospital of Shanghai.

作者信息

Zhao X, Ni B, Wang Y, Shen X, Zhang C, Liu J, Li S

机构信息

Microbiology Laboratory,Centre for Disease Control and Prevention of Xuhui,Xuhui District,Shanghai,China.

出版信息

Epidemiol Infect. 2017 Feb;145(3):545-552. doi: 10.1017/S0950268816002533. Epub 2016 Nov 3.

Abstract

Epidemic surveillance is an effective means to determine the characteristics of acute diarrhoea and the benefits of disease control and prevention. The epidemiological, clinical, and aetiological data of adult (aged ⩾15 years) acute diarrhoea in a general hospital in Shanghai were collected and analysed. Out of 2430 acute diarrhoea patients, 162 subjects were sampled (sample ratio 15:1). The sampled subjects had an average age (±s.d.) of 44 ± 18 years; 142 (87·7%) had a history that indicated ingestion of contaminated food; and 40 (24·7%), 54 (33·3%), and 73 (45·1%) patients had diarrhoea that was attributed to viral, bacterial, and unknown aetiological origins respectively. Viral diarrhoea is mainly prevalent during the winter and spring months, while bacterial and diarrhoea of unknown aetiology occur mainly in the summer months. The average age of the unknown aetiology group (48 ± 19 years) was significantly older than that of the viral diarrhoea group (39 ± 16 years). The number of patients with vomiting in the viral group (30·6%) was significantly higher than that in the bacterial (17·1%) and unknown aetiology (8·2%) groups. Viral and bacterial infections are the main cause of acute diarrhoea in Shanghai. However, further effective technological means are needed to improve the surveillance, control, and prevention of acute diarrhoea.

摘要

疫情监测是确定急性腹泻特征以及疾病防控效益的有效手段。收集并分析了上海某综合医院成年(年龄≥15岁)急性腹泻患者的流行病学、临床和病因学数据。在2430例急性腹泻患者中,抽取了162例受试者(抽样比例为15:1)。抽样受试者的平均年龄(±标准差)为44±18岁;142例(87.7%)有摄入受污染食物的病史;分别有40例(24.7%)、54例(33.3%)和73例(45.1%)患者的腹泻归因于病毒、细菌和病因不明。病毒性腹泻主要在冬春季节流行,而细菌性腹泻和病因不明的腹泻主要发生在夏季。病因不明组的平均年龄(48±19岁)显著高于病毒性腹泻组(39±16岁)。病毒组呕吐患者的数量(30.6%)显著高于细菌组(17.1%)和病因不明组(8.2%)。病毒和细菌感染是上海急性腹泻的主要原因。然而,需要进一步有效的技术手段来加强急性腹泻的监测、控制和预防。

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