2009 - 2012年印度5岁以下住院儿童轮状病毒腹泻的多中心监测

Multi-center surveillance of rotavirus diarrhea in hospitalized children <5 years of age in India, 2009-2012.

作者信息

Babji Sudhir, Arumugam Rajesh, Sarvanabhavan Anuradha, Moses Prabhakar D, Simon Anna, Aggarwal Indira, Mathew Ann, Kang Gagandeep

机构信息

Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India.

Department of Child Health, Christian Medical College, Vellore, India.

出版信息

Vaccine. 2014 Aug 11;32 Suppl 1:A10-2. doi: 10.1016/j.vaccine.2014.03.001.

DOI:10.1016/j.vaccine.2014.03.001

PMID:25091661

Abstract

Diarrheal disease due to Group A rotaviruses continues to be an important cause of morbidity in the developing world and India contributes significantly to the disease burden. Surveillance carried out between July 2009 and June 2012 at two medical centers in south India and one center in north India estimated 39% of all diarrheal admissions to be due to rotavirus. The most prevalent genotype isolated was G1P8 followed by G2P4. G9P[4] has also emerged as a significant cause of rotavirus diarrhea. No seasonal variation was noticed from the centers in south India, whereas we observed increased rotavirus diarrhea in the center in north India during March and April.

摘要

A组轮状病毒引起的腹泻病仍然是发展中世界发病的一个重要原因，印度对该病负担的贡献很大。2009年7月至2012年6月期间在印度南部的两个医疗中心和印度北部的一个中心进行的监测估计，所有腹泻住院病例中有39%是由轮状病毒引起的。分离出的最常见基因型是G1P8，其次是G2P4。G9P[4]也已成为轮状病毒腹泻的一个重要原因。印度南部各中心未发现季节性变化，而我们观察到印度北部的中心在3月和4月期间轮状病毒腹泻有所增加。