与IgLON5自身抗体相关且对免疫治疗有反应的舞蹈症和帕金森症。
Chorea and parkinsonism associated with autoantibodies to IgLON5 and responsive to immunotherapy.
作者信息
Haitao Ren, Yingmai Yang, Yan Huang, Fei Han, Xia Lv, Honglin Hao, Chaiyan Liu, Stöcker Winfried, Liying Cui, Hongzhi Guan
机构信息
Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
Institute for Experimental Immunology, Euroimmun AG, Lübeck, Germany.
出版信息
J Neuroimmunol. 2016 Nov 15;300:9-10. doi: 10.1016/j.jneuroim.2016.09.012. Epub 2016 Sep 24.
Encephalopathy associated with autoantibodies to IgLON5 is a novel syndrome characterized by a distinct sleep disorder and brain-stem involvement. Since the initial description of this encephalopathy in 2014, only a few additional patients have been reported (Simabukuro et al., 2015). In this paper, we report a new case of anti-IgLON5 antibodies with major symptoms of chorea and parkinsonism, and responsive to immunotherapy.
与IgLON5自身抗体相关的脑病是一种新型综合征，其特征为独特的睡眠障碍和脑干受累。自2014年首次描述这种脑病以来，仅有少数其他患者被报道（Simabukuro等人，2015年）。在本文中，我们报告了一例以舞蹈症和帕金森症为主要症状且对免疫疗法有反应的抗IgLON5抗体新病例。
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