• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Early immunotherapy is highly effective in IgG1/IgG4 positive IgLON5 disease.

作者信息

Grüter Thomas, Behrendt Volker, Bien Corinna I, Gold Ralf, Ayzenberg Ilya

机构信息

Department of Neurology, St. Josef Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791, Bochum, Germany.

Laboratory Krone, Siemensstr. 40, 32105, Bad Salzuflen, Germany.

出版信息

J Neurol. 2020 Jul;267(7):2151-2153. doi: 10.1007/s00415-020-09924-y. Epub 2020 May 22.

DOI:10.1007/s00415-020-09924-y
PMID:32444985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7320942/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed66/7320942/c5362eba0fa7/415_2020_9924_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed66/7320942/c5362eba0fa7/415_2020_9924_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed66/7320942/c5362eba0fa7/415_2020_9924_Fig1_HTML.jpg

相似文献

1
Early immunotherapy is highly effective in IgG1/IgG4 positive IgLON5 disease.早期免疫疗法对IgG1/IgG4阳性的IgLON5疾病非常有效。
J Neurol. 2020 Jul;267(7):2151-2153. doi: 10.1007/s00415-020-09924-y. Epub 2020 May 22.
2
Cellular investigations with human antibodies associated with the anti-IgLON5 syndrome.与抗IgLON5综合征相关的人类抗体的细胞研究。
J Neuroinflammation. 2016 Sep 1;13(1):226. doi: 10.1186/s12974-016-0689-1.
3
Clinical manifestations of the anti-IgLON5 disease.抗IgLON5疾病的临床表现。
Neurology. 2017 May 2;88(18):1736-1743. doi: 10.1212/WNL.0000000000003887. Epub 2017 Apr 5.
4
Teaching Video NeuroImages: Anti-IgLON5 Disease: A Long-Course Presentation With a Response to Immunotherapy.教学视频神经影像：抗IgLON5疾病：长期病程表现及免疫治疗反应
Neurology. 2021 Jun 8;96(23):e2901-e2902. doi: 10.1212/WNL.0000000000011381. Epub 2020 Dec 22.
5
Delayed Benefit From Aggressive Immunotherapy in Waxing and Waning Anti-IgLON5 Disease.在病情反复的抗IgLON5病中积极免疫治疗的延迟获益
Neurol Neuroimmunol Neuroinflamm. 2021 May 13;8(4). doi: 10.1212/NXI.0000000000001009. Print 2021 Jul.
6
Immunotherapy improves sleep and cognitive impairment in anti-IgLON5 encephalopathy.免疫疗法可改善抗IgLON5脑病患者的睡眠和认知障碍。
Neurol Neuroimmunol Neuroinflamm. 2019 May 21;6(4):e577. doi: 10.1212/NXI.0000000000000577. eCollection 2019 Jul.
7
[Effect of immunotherapy on house dust mite allergen-specific IgG1 and igG4 antibodies in nasal secretion for patients with perennial allergic rhinitis].[免疫疗法对常年性变应性鼻炎患者鼻分泌物中屋尘螨变应原特异性IgG1和IgG4抗体的影响]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004 Dec;39(12):725-9.
8
Intravenous immunoglobulins as first-line therapy for IgLON5 encephalopathy.静脉注射免疫球蛋白作为IgLON5脑病的一线治疗方法。
J Neurol. 2019 Apr;266(4):1031-1033. doi: 10.1007/s00415-019-09221-3. Epub 2019 Feb 8.
9
Diagnosis and immunotherapy of mould allergy. VII. IgG subclass response and relation to the clinical efficacy of immunotherapy with Cladosporium.霉菌过敏的诊断与免疫疗法。VII. IgG亚类反应及其与枝孢菌免疫疗法临床疗效的关系。
Allergy. 1988 Jan;43(1):60-70. doi: 10.1111/j.1398-9995.1988.tb02045.x.
10
IgG4-Mediated Neurologic Autoimmunities: Understanding the Pathogenicity of IgG4, Ineffectiveness of IVIg, and Long-Lasting Benefits of Anti-B Cell Therapies.IgG4 相关的神经免疫性疾病：认识 IgG4 的致病性、IVIg 的无效性和抗 B 细胞治疗的持久获益。
Neurol Neuroimmunol Neuroinflamm. 2021 Nov 29;9(1). doi: 10.1212/NXI.0000000000001116. Print 2022 Jan.

引用本文的文献

1
Early Treatment With Intravenous Immunoglobulins and Outcomes of Patients With Anti-IgLON5 Disease.静脉注射免疫球蛋白早期治疗与抗IgLON5病患者的预后
JAMA Neurol. 2025 Aug 4. doi: 10.1001/jamaneurol.2025.2574.
2
Acute onset of anti-IgLON5 disease with meningeal enhancement: a case report.伴有脑膜强化的抗IgLON5病急性起病：一例报告
BMC Neurol. 2025 Mar 5;25(1):86. doi: 10.1186/s12883-025-04104-9.
3
The Importance of Bright Spotty Lesions on Magnetic Resonance Imaging in Predicting Chronic Neuropathic Pain in Myelitis.

本文引用的文献

1
Neurological profiles beyond the sleep disorder in patients with anti-IgLON5 disease.抗 IgLON5 病患者除睡眠障碍外的神经学特征。
Curr Opin Neurol. 2019 Jun;32(3):493-499. doi: 10.1097/WCO.0000000000000677.
2
Anti-IgLON5 Disease Responsive to Immunotherapy: A Case Report with an Abnormal MRI.对免疫疗法有反应的抗IgLON5疾病：一例伴有MRI异常的病例报告
Mov Disord Clin Pract. 2018 Nov 8;5(6):653-656. doi: 10.1002/mdc3.12679. eCollection 2018 Nov-Dec.
3
IgLON5-Associated Encephalitis With Atypical Brain Magnetic Resonance Imaging and Cerebrospinal Fluid Changes.
磁共振成像上的亮点状病变在预测脊髓炎慢性神经性疼痛中的重要性
J Clin Med. 2024 Dec 21;13(24):7820. doi: 10.3390/jcm13247820.
4
The psychiatric symptoms in anti-IgLON5 disease: Case report and literature review.抗IgLON5疾病中的精神症状：病例报告与文献综述
Clin Case Rep. 2024 Jan 12;12(1):e8310. doi: 10.1002/ccr3.8310. eCollection 2024 Jan.
5
Sleep Disturbances in Autoimmune Neurological Diseases.自身免疫性神经疾病中的睡眠障碍
Curr Neurol Neurosci Rep. 2023 Oct;23(10):617-625. doi: 10.1007/s11910-023-01294-y. Epub 2023 Sep 6.
6
Thinking beyond otorhinolaryngology in patients presenting with bilateral vocal cord paresis.对于双侧声带麻痹患者，跳出耳鼻喉科的局限进行思考。
J Surg Case Rep. 2023 Mar 30;2023(3):rjad140. doi: 10.1093/jscr/rjad140. eCollection 2023 Mar.
7
Anti-IgLON5 Disease with Isolated Hemichorea: A Case Report and Review of the Literature.伴孤立性偏侧舞蹈症的抗IgLON5病：一例报告及文献复习
Mov Disord Clin Pract. 2022 Nov 24;10(1):115-119. doi: 10.1002/mdc3.13614. eCollection 2023 Jan.
8
Anti-IgLON5 disease complicated with rectal adenocarcinoma: a case report.抗 IgLON5 病并发直肠腺癌：病例报告。
BMC Neurol. 2023 Jan 3;23(1):1. doi: 10.1186/s12883-022-03044-y.
9
Anti-IgLON5 disease: a novel topic beyond neuroimmunology.抗IgLON5病：神经免疫学之外的一个新课题。
Neural Regen Res. 2023 May;18(5):1017-1022. doi: 10.4103/1673-5374.355742.
10
Autoimmune and Paraneoplastic Chorea: A Review of the Literature.自身免疫性和副肿瘤性舞蹈病：文献综述
Front Neurol. 2022 Mar 18;13:829076. doi: 10.3389/fneur.2022.829076. eCollection 2022.
伴有非典型脑磁共振成像及脑脊液改变的IgLON5相关脑炎
Front Neurol. 2018 May 17;9:329. doi: 10.3389/fneur.2018.00329. eCollection 2018.
4
IgLON5 antibody: Neurological accompaniments and outcomes in 20 patients.IgLON5抗体：20例患者的神经学伴随症状及转归
Neurol Neuroimmunol Neuroinflamm. 2017 Jul 18;4(5):e385. doi: 10.1212/NXI.0000000000000385. eCollection 2017 Sep.
5
Clinical manifestations of the anti-IgLON5 disease.抗IgLON5疾病的临床表现。
Neurology. 2017 May 2;88(18):1736-1743. doi: 10.1212/WNL.0000000000003887. Epub 2017 Apr 5.
6
Chorea and parkinsonism associated with autoantibodies to IgLON5 and responsive to immunotherapy.与IgLON5自身抗体相关且对免疫治疗有反应的舞蹈症和帕金森症。
J Neuroimmunol. 2016 Nov 15;300:9-10. doi: 10.1016/j.jneuroim.2016.09.012. Epub 2016 Sep 24.
7
A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study.一种新型非快速眼动和快速眼动睡眠障碍相关呼吸暂停与 IgLON5 抗体相关：病例系列、抗原特征和尸检研究。
Lancet Neurol. 2014 Jun;13(6):575-86. doi: 10.1016/S1474-4422(14)70051-1. Epub 2014 Apr 3.