Carrasco-Llatas Marina, Zerpa-Zerpa Vanessa, Dalmau-Galofre José
Hospital Universitario Dr. Peset, Valencia, Spain.
Sleep Breath. 2017 Mar;21(1):173-179. doi: 10.1007/s11325-016-1426-9. Epub 2016 Nov 3.
Several studies have demonstrated the validity, reliability, and safety of drug-induced sedation endoscopy (DISE) in assessing the collapse of the upper airway (UA) in patients with obstructive sleep apnea hypoapnea syndrome (OSAHS). The aim of this study was to assess the interobserver agreement on DISE and on therapeutic decision between an expert observer and an observer in training.
This was a cross-sectional study. Thirty-one DISE videos performed in our service were randomly selected. Videos belonged to patients with OSAHS who wanted alternative treatments to CPAP. The videos were reviewed by an ENT experienced on DISE and a second observer in formation. Each observer independently assessed the presence of collapse of the UA according to a modified VOTE classification and proposed an alternative treatment to CPAP. Interobserver agreement kappa values were calculated.
In assessing the presence of collapse at different levels of the upper airway, the percentage of agreement was 80 % at the level of the soft palate (kappa = 0.1667), 89.29 % in the oropharynx (k = 0.7742), 80.65 % at the tongue base (k = 0.5571), and 74.17 % at the epiglottis (k = 0.4768). When degree and configuration of the collapse was evaluated, the interrater agreement was moderate to good, except at the level of the tongue base where the agreement was weak for both degree and configuration of collapse (k = 0.34 and 0.38, respectively). Interobserver agreement was moderate when the indication of alternative treatments to CPAP is valued based on the findings of DISE.
Overall, DISE is a reliable technique even when assessing interobserver agreement between an experienced observer and one in training; however, tongue base is the level of the upper airway that presents the greatest difficulties when assessing the collapse with DISE. Therefore, it is important to develop learning curves for this technique in order to obtain more reliable results.
多项研究已证实药物诱导镇静内镜检查(DISE)在评估阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者上气道(UA)塌陷方面的有效性、可靠性和安全性。本研究的目的是评估专家观察者与实习观察者之间在DISE及治疗决策上的观察者间一致性。
这是一项横断面研究。随机选取了在我们科室进行的31份DISE视频。这些视频来自希望接受CPAP替代治疗的OSAHS患者。由一位DISE经验丰富的耳鼻喉科医生和一位实习观察者对视频进行评估。每位观察者根据改良的VOTE分类独立评估UA塌陷的存在情况,并提出CPAP的替代治疗方案。计算观察者间一致性kappa值。
在评估上气道不同水平塌陷的存在情况时,软腭水平的一致性百分比为80%(kappa = 0.1667),口咽水平为89.29%(k = 0.7742),舌根水平为80.65%(k = 0.5571),会厌水平为74.17%(k = 0.4768)。在评估塌陷的程度和形态时,观察者间一致性为中等至良好,但在舌根水平,塌陷程度和形态的一致性均较弱(分别为k = 0.34和0.38)。根据DISE结果评估CPAP替代治疗的指征时,观察者间一致性为中等。
总体而言,即使在评估经验丰富的观察者与实习观察者之间的观察者间一致性时,DISE也是一项可靠的技术;然而,舌根是使用DISE评估塌陷时上气道中最具困难的水平。因此,为该技术绘制学习曲线以获得更可靠的结果很重要。