Lou Cunguang, Li Ruikai, Li Zhaopeng, Liang Tie, Wei Zihui, Run Mingtao, Yan Xiaobing, Liu Xiuling
Department of Biomedical Engineering, College of Electronic Information Engineering & Key Laboratory of Digital Medical Engineering of Hebei Province, Hebei University, Baoding 071002, China.
College of Quality and Technical Supervision, Hebei University, Baoding 071002, China.
Sensors (Basel). 2016 Nov 1;16(11):1833. doi: 10.3390/s16111833.
This paper describes the development of a graphene-based dry flexible electrocardiography (ECG) electrode and a portable wireless ECG measurement system. First, graphene films on polyethylene terephthalate (PET) substrates and graphene paper were used to construct the ECG electrode. Then, a graphene textile was synthesized for the fabrication of a wearable ECG monitoring system. The structure and the electrical properties of the graphene electrodes were evaluated using Raman spectroscopy, scanning electron microscopy (SEM), and alternating current impedance spectroscopy. ECG signals were then collected from healthy subjects using the developed graphene electrode and portable measurement system. The results show that the graphene electrode was able to acquire the typical characteristics and features of human ECG signals with a high signal-to-noise (SNR) ratio in different states of motion. A week-long continuous wearability test showed no degradation in the ECG signal quality over time. The graphene-based flexible electrode demonstrates comfortability, good biocompatibility, and high electrophysiological detection sensitivity. The graphene electrode also combines the potential for use in long-term wearable dynamic cardiac activity monitoring systems with convenience and comfort for use in home health care of elderly and high-risk adults.
本文描述了一种基于石墨烯的干式柔性心电图（ECG）电极及便携式无线心电图测量系统的研发。首先，利用聚对苯二甲酸乙二酯（PET）基底上的石墨烯薄膜和石墨烯纸构建心电图电极。然后，合成了一种用于制造可穿戴式心电图监测系统的石墨烯织物。使用拉曼光谱、扫描电子显微镜（SEM）和交流阻抗谱对石墨烯电极的结构和电学性能进行了评估。随后，使用所研发的石墨烯电极和便携式测量系统从健康受试者采集心电图信号。结果表明，石墨烯电极能够在不同运动状态下以高信噪比（SNR）获取人体心电图信号的典型特征。为期一周的连续可穿戴性测试表明，随着时间推移心电图信号质量没有下降。基于石墨烯的柔性电极展现出舒适性、良好的生物相容性和高电生理检测灵敏度。该石墨烯电极还兼具用于长期可穿戴动态心脏活动监测系统的潜力以及便于在老年人和高危成年人家庭医疗保健中使用的舒适性。
