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[氧化氚或γ射线长期作用后大鼠的免疫指标]

[The immunity indices of rats after the long-term action of tritium oxide or gamma irradiation].

作者信息

Kirillova E N

出版信息

Radiobiologiia. 1990 Mar-Apr;30(2):175-8.

PMID:2349375
Abstract

In experiments with Wistar rats, a study was made of the content of antibody-forming cells and cytotoxic activity of normal killers after long-term administration of tritium oxide (3HOH) (370 kBq.g-1 of body mass daily, cumulative dose, 8.1 Gy, and dose rate, 8.5 cGy/day), and after gamma irradiation with corresponding doses. The long-term radiation effect caused a decrease in the immunity indices: the impairment of the immune reactions was more pronounced after the effect of 3HOH than after gamma irradiation. Damages to the immune system of mice and rats after irradiation with similar doses were compared.

摘要

在对Wistar大鼠进行的实验中,研究了长期给予氧化氚(3HOH)(每天370 kBq·g-1体重,累积剂量8.1 Gy,剂量率8.5 cGy/天)后以及相应剂量γ射线照射后抗体形成细胞的含量和正常杀伤细胞的细胞毒性活性。长期辐射效应导致免疫指标下降:3HOH作用后免疫反应的损害比γ射线照射后更明显。比较了相似剂量照射后小鼠和大鼠免疫系统的损伤情况。

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