米非司酮与阴道用米索前列醇在不同孕周终止早期妊娠的比较研究
Comparative Study of Mifepristone with Vaginal Misoprostol for First Trimester Termination of Pregnancy at Different Gestational Ages.
作者信息
Meena Seema Rani
机构信息
District Hospital, Sawai Madhopur, Rajasthan India.
出版信息
J Obstet Gynaecol India. 2016 Dec;66(6):426-430. doi: 10.1007/s13224-015-0705-x. Epub 2015 Jun 14.
METHODS
This study for medical abortion was conducted in the Department of Obstetrics and Gynaecology, Zenana Hospital, SMS Medical College, Jaipur during 2011-2012. In total 280 cases were taken for the study and divided into two groups, among whom there were six defaulters in each group who failed to present for follow-up.
OBJECTIVES
The objectives of this study were to (1) compare the success rates of abortion at different gestational ages, (2) study the side effects of the drugs, and (3) study the acceptability in both the groups.
RESULTS
The medical abortion with the given regimen and protocol was observed to be highly successful, and complete abortion was achieved in 98.51 and 97.76 % of the patients in Group-A and Group-B, respectively. Failure rates observed were only 1.49 % in Group-A and 2.24 % in Group-B.
CONCLUSIONS
Medical abortion can be safely performed in cases up to 63 days of gestation, but women should be counseled about the increased blood loss and duration of bleeding.
方法
本药物流产研究于2011年至2012年在斋浦尔SMS医学院齐纳纳医院妇产科进行。共选取280例病例进行研究，分为两组，每组有6例失访者未前来接受随访。
目的
本研究的目的是（1）比较不同孕周的流产成功率，（2）研究药物的副作用，（3）研究两组的可接受性。
结果
观察到采用给定方案和规程进行的药物流产非常成功，A组和B组分别有98.51%和97.76%的患者实现了完全流产。观察到的失败率在A组仅为1.49%，在B组为2.24%。
结论
妊娠63天以内的病例可以安全地进行药物流产，但应向女性咨询有关失血增加和出血持续时间的问题。
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