Snowden Jonathan M, Muoto Ifeoma, Darney Blair G, Quigley Brian, Tomlinson Mark W, Neilson Duncan, Friedman Steven A, Rogovoy Joanne, Caughey Aaron B
Departments of Obstetrics and Gynecology and Public Health & Preventive Medicine, Oregon Health & Science University, Providence Health & Services, Legacy Health, Kaiser Permanente, Northwest Region, and the March of Dimes, Portland, Oregon; and the Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.
Obstet Gynecol. 2016 Dec;128(6):1389-1396. doi: 10.1097/AOG.0000000000001737.
To evaluate the association of Oregon's hard-stop policy limiting early elective deliveries (before 39 weeks of gestation) and the rate of elective early-term inductions and cesarean deliveries and associated maternal-neonatal outcomes.
This was a population-based retrospective cohort study of Oregon births between 2008 and 2013 using vital statistics data and multivariable logistic regression models. Our exposure was the Oregon hard-stop policy, defined as the time periods prepolicy (2008-2010) and postpolicy (2012-2013). We included all term or postterm, cephalic, nonanomalous, singleton deliveries (N=181,034 births). Our primary outcomes were induction of labor and cesarean delivery at 37 or 38 weeks of gestation without a documented indication on the birth certificate (ie, elective early term delivery). Secondary outcomes included neonatal intensive care unit admission, stillbirth, macrosomia, chorioamnionitis, and neonatal death.
The rate of elective inductions before 39 weeks of gestation declined from 4.0% in the prepolicy period to 2.5% during the postpolicy period (P<.001); a similar decline was observed for elective early-term cesarean deliveries (from 3.4% to 2.1%; P<.001). There was no change in neonatal intensive care unit admission, stillbirth, or assisted ventilation prepolicy and postpolicy, but chorioamnionitis did increase (from 1.2% to 2.2%, P<.001; adjusted odds ratio 1.94, 95% confidence interval 1.80-2.09).
Oregon's statewide policy to limit elective early-term delivery was associated with a reduction in elective early-term deliveries, but no improvement in maternal or neonatal outcomes.
评估俄勒冈州限制早期选择性分娩(妊娠39周前)的硬终止政策与选择性早期引产和剖宫产率以及相关母婴结局之间的关联。
这是一项基于人群的回顾性队列研究,利用生命统计数据和多变量逻辑回归模型,对2008年至2013年俄勒冈州的出生情况进行研究。我们的暴露因素是俄勒冈州的硬终止政策,定义为政策实施前时期(2008 - 2010年)和政策实施后时期(2012 - 2013年)。我们纳入了所有足月或过期、头位、无异常、单胎分娩(N = 181,034例出生)。我们的主要结局是在妊娠37或38周时无出生证明上记录的指征的引产和剖宫产(即选择性早期足月分娩)。次要结局包括新生儿重症监护病房入院、死产、巨大儿、绒毛膜羊膜炎和新生儿死亡。
妊娠39周前的选择性引产率从政策实施前时期的4.0%降至政策实施后时期的2.5%(P <.001);选择性早期足月剖宫产也有类似下降(从3.4%降至2.1%;P <.001)。政策实施前和实施后,新生儿重症监护病房入院、死产或辅助通气情况没有变化,但绒毛膜羊膜炎确实增加了(从1.2%增至2.2%,P <.001;调整后的优势比为1.94,95%置信区间为1.80 - 2.09)。
俄勒冈州限制选择性早期足月分娩的全州性政策与选择性早期足月分娩的减少有关,但母婴结局并未改善。