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前列腺癌的诊断与治疗策略

Diagnostic and Therapeutic Strategies for Prostate Cancer.

作者信息

Nguyen-Nielsen Mary, Borre Michael

机构信息

Department of Urology, Aarhus University Hospital, Aarhus, Denmark; Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.

Department of Urology, Aarhus University Hospital, Aarhus, Denmark.

出版信息

Semin Nucl Med. 2016 Nov;46(6):484-490. doi: 10.1053/j.semnuclmed.2016.07.002. Epub 2016 Sep 3.

Abstract

Prostate cancer (PC) is a major disease that affects men's health worldwide. It is the second most common form of cancer in men, surpassed only by nonmelanoma skin cancers such as basal and squamous cell carcinomas. Diagnostic strategies with population screening for prostate cancer using prostate-specific antigen (PSA) has been surrounded with controversy and debated intensively ever since the PSA protein was first purified in 1979 by Wang et al. At the same time, advances in diagnostic imaging, surgery, radiation, and chemotherapy have increased the opportunity to effectively diagnose, treat, and manage PC. Given the sheer burden of PC disease in Denmark and worldwide, new and innovative strategies for cancer diagnosis and care are needed. This article is a short review of current diagnostic and therapeutic strategies for the care and management of prostate cancer in Denmark.

摘要

前列腺癌(PC)是一种影响全球男性健康的主要疾病。它是男性中第二常见的癌症形式,仅次于诸如基底细胞癌和鳞状细胞癌等非黑色素瘤皮肤癌。自1979年Wang等人首次纯化前列腺特异性抗原(PSA)以来,使用PSA对前列腺癌进行人群筛查的诊断策略一直备受争议并引发了激烈辩论。与此同时,诊断成像、手术、放疗和化疗方面的进展增加了有效诊断、治疗和管理前列腺癌的机会。鉴于丹麦乃至全球前列腺癌疾病的沉重负担,需要新的创新性癌症诊断和护理策略。本文是对丹麦前列腺癌护理和管理的当前诊断和治疗策略的简要综述。

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