El-Mayah Esraa, Albalkini Ahmed Saad, Barrada Omar A
Ophthalmology Department, Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.
Clin Ophthalmol. 2024 Mar 21;18:901-912. doi: 10.2147/OPTH.S451328. eCollection 2024.
To characterize corneal biomechanical properties using the CORVIS-ST device in myopic individuals.
This prospective cross-sectional study included patients with myopia. Our study included 154 eyes of 154 myopic patients aged between 18 and 40 years, with stable refraction for at least 2 years. A full ophthalmological examination and corneal tomography were performed using a Pentacam HR device. Corneal biomechanical parameters were assessed using the CORVIS-ST device in mild, moderate, severe, and extreme myopia groups.
Statistically significant differences were observed in the DA ratio (p = 0.033), SP-A (p=0.009), CBI (p=0.041), SSI (p=0.000), and Peak distance (p = 0.032). In correlation with different Corvis ST biomechanical variables, SE was found to be correlated with DA ratio(r=-0.191, p=0.018), SP-A(r=0.199, p=0.013) and SSI(r=-0.336, p=0.000), while in multiple regression analysis, SE was found to be independently correlated with SSI and peak distance(p=0.036,0.038 respectively) while the grade of myopia was found to be independently correlated with SP-A(p=0.034).
SSI, Peak distance, and SP-A were independently related to SE and myopia grade, confirming the hypothesis that eyes with higher myopia are more deformable and less stress resistant.
使用CORVIS-ST设备对近视患者的角膜生物力学特性进行表征。
这项前瞻性横断面研究纳入了近视患者。我们的研究包括154例年龄在18至40岁之间、屈光稳定至少2年的近视患者的154只眼。使用Pentacam HR设备进行全面的眼科检查和角膜断层扫描。在轻度、中度、重度和极高度近视组中,使用CORVIS-ST设备评估角膜生物力学参数。
在DA比率(p = 0.033)、SP-A(p = 0.009)、CBI(p = 0.041)、SSI(p = 0.000)和峰值距离(p = 0.032)方面观察到统计学上的显著差异。与不同的Corvis ST生物力学变量相关,发现SE与DA比率(r = -0.191,p = 0.018)、SP-A(r = 0.199,p = 0.013)和SSI(r = -0.336,p = 0.000)相关,而在多元回归分析中,发现SE与SSI和峰值距离独立相关(分别为p = 0.036,0.038),而近视度数与SP-A独立相关(p = 0.034)。
SSI、峰值距离和SP-A与SE和近视度数独立相关,证实了高度近视眼睛更易变形且抗应力能力更弱的假设。