Kenia Vaishal P, Kenia Raj V, Bendre Pradnya, Pirdankar Onkar H
Department of Cataract and Refractive Surgery, Kenia Eye Hospital, Mumbai, Maharashtra, India.
Department of Ophthalmology, Kenia Foundation, Mumbai, Maharashtra, India.
Oman J Ophthalmol. 2024 Feb 21;17(1):47-52. doi: 10.4103/ojo.ojo_122_23. eCollection 2024 Jan-Apr.
The purpose is to study the corneal stress-strain index (SSI) in myopic refractive error among Indian subjects.
A retrospective study where young myopic subjects aged between 11 and 35 years who had undergone corneal biomechanics assessment using Corvis ST between January 2017 and December 2021 were enrolled. Subjects with central corneal thickness (CCT) <500 μ, intraocular pressure (IOP) >21 mmHg, history of any systemic and ocular disease or any previous ocular surgery, high astigmatism, corneal disease such as keratoconus were excluded. Subjects with missing data or having poor quality scan were excluded. Corneal biomechanical properties and corneal SSI were assessed using Corvis ST. For statistical purposes, eyes were divided into four different groups and were analyzed using one-way ANOVA.
Nine hundred and sixty-six myopic eyes with mean ± standard deviation age, IOP, and CCT of 26.89 ± 4.92 years, 16.94 ± 2.00 mmHg, and 540.18 ± 25.23 microns, respectively, were included. There were 311, 388, 172, and 95 eyes that were low, moderate, severe, and extreme myopic. Deformation amplitude ratio at 1 mm and 2 mm were similar across different myopic groups. A significant increase in max inverse radius, ambrosia relational thickness, biomechanically corrected IOP, integrated radius was noted with an increase in myopic refractive error. Corvis biomechanical index, corneal SSI was found to be decreased significantly with an increase in myopic refractive error. We noted a significant positive association between myopic refractive error and SSI ( < 0.001).
Corneal SSI was found to be reduced in extreme myopic eyes.
旨在研究印度受试者近视屈光不正中的角膜应力应变指数（SSI）。
一项回顾性研究，纳入了2017年1月至2021年12月期间使用Corvis ST进行角膜生物力学评估的11至35岁的年轻近视受试者。排除中央角膜厚度（CCT）<500μm、眼压（IOP）>21mmHg、有任何全身和眼部疾病史或任何既往眼部手术史、高度散光、圆锥角膜等角膜疾病的受试者。排除数据缺失或扫描质量差的受试者。使用Corvis ST评估角膜生物力学特性和角膜SSI。为了进行统计，将眼睛分为四个不同的组，并使用单因素方差分析进行分析。
纳入了966只近视眼睛，其平均年龄±标准差、眼压和中央角膜厚度分别为26.89±4.92岁、16.94±2.00mmHg和540.18±25.23微米。低度、中度、重度和极高度近视的眼睛分别有311只、388只、172只和95只。不同近视组在1mm和2mm处的变形幅度比相似。随着近视屈光不正的增加，最大反半径、神经营养相关厚度、生物力学校正眼压、积分半径显著增加。发现随着近视屈光不正的增加，Corvis生物力学指数、角膜SSI显著降低。我们注意到近视屈光不正与SSI之间存在显著正相关（<0.001）。
发现极高度近视眼中的角膜SSI降低。
