中年男性血清胆固醇酯成分、饮食习惯与冠心病危险因素之间的关系。

Relationship between serum cholesteryl ester composition, dietary habits and coronary risk factors in middle-aged men.

作者信息

De Backer G, De Craene I, Rosseneu M, Vercaemst R, Kornitzer M

机构信息

Department of Hygiene and Social Medicine, University Hospital Ghent, Belgium.

出版信息

Atherosclerosis. 1989 Aug;78(2-3):237-43. doi: 10.1016/0021-9150(89)90229-3.

DOI:10.1016/0021-9150(89)90229-3

PMID:2783205

Abstract

Serum cholesteryl palmitate, oleate, linoleate and arachidonate were measured using high performance liquid chromatography in 134 men aged 45-64 years, randomly selected from the population of Ghent, Belgium. No relationship was observed between these cholesteryl esters, expressed as a percentage of their total, and age, serum cholesterol, arterial blood pressure, smoking habits and body mass index. Dietary habits were assessed using a 3-day diary method. No relationship was found between dietary habits and serum lipids. Highly significant correlations were observed between diet and the serum cholesteryl esters. In multivariate analyses dietary variables account for significant proportions of the variances of the serum cholesteryl esters. The results indicate that measurements of cholesteryl esters can be used to differentiate on the population level between subgroups with different dietary habits particularly with respect to fat consumption.

摘要

采用高效液相色谱法对从比利时根特市人群中随机选取的134名45至64岁男性的血清棕榈酸胆固醇酯、油酸胆固醇酯、亚油酸胆固醇酯和花生四烯酸胆固醇酯进行了测定。未观察到这些胆固醇酯（以其总量的百分比表示）与年龄、血清胆固醇、动脉血压、吸烟习惯和体重指数之间存在关联。饮食习惯采用3天日记法进行评估。未发现饮食习惯与血脂之间存在关联。观察到饮食与血清胆固醇酯之间存在高度显著的相关性。在多变量分析中，饮食变量占血清胆固醇酯方差的很大比例。结果表明，胆固醇酯的测量可用于在人群水平上区分具有不同饮食习惯（特别是在脂肪摄入方面）的亚组。