Celiac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands.
Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield S10 2JF, UK.
Nutrients. 2016 Nov 8;8(11):714. doi: 10.3390/nu8110714.
A growing number of individuals reports symptoms related to the ingestion of gluten-containing food in the absence of celiac disease. Yet the actual prevalence is not well established.
Between April 2015 and March 2016, unselected adults visiting marketplaces, dental practices and a university in The Netherlands were asked to complete a modified validated questionnaire for self-reported gluten sensitivity (srGS).
Among the 785 adults enquired, two had celiac disease. Forty-nine (6.2%) reported symptoms related to the ingestion of gluten-containing food. These individuals were younger, predominantly female and lived more frequently in urban regions compared with the other respondents. Symptoms reported included bloating (74%), abdominal discomfort (49%) and flatulence (47%). A total of 23 (47%) srGS individuals reported having had tried a gluten-free or gluten-restricted diet. Abdominal discomfort related to fermentable oligosaccharide, disaccharide, monosaccharide and polyol (FODMAP)-containing food was more often reported in srGS individuals compared with the other respondents (73.5% vs. 21.7%, 0.001).
Self-reported GS is common in The Netherlands, especially in younger individuals, females and urban regions, although the prevalence was lower than in a comparable recent UK study. It cannot be excluded that FODMAPs are in part responsible for these symptoms.
越来越多的人报告称，在没有乳糜泻的情况下，摄入含麸质的食物会出现相关症状。然而，实际的患病率尚未得到很好的确立。
在 2015 年 4 月至 2016 年 3 月期间，荷兰的市场、牙科诊所和一所大学的未选择的成年人被要求填写一份经过修改的、经过验证的、用于自述麸质敏感性（srGS）的问卷。
在被询问的 785 名成年人中，有两人患有乳糜泻。49 人（6.2%）报告称摄入含麸质的食物后出现相关症状。这些人比其他受访者更年轻，主要是女性，并且更频繁地居住在城市地区。报告的症状包括腹胀（74%）、腹部不适（49%）和肠胃气胀（47%）。共有 23 名（47%）srGS 个体报告曾尝试过无麸质或限制麸质的饮食。与其他受访者相比，srGS 个体更常报告与可发酵寡糖、双糖、单糖和多元醇（FODMAP）含量食物相关的腹部不适（73.5% vs. 21.7%，0.001）。
在荷兰，自述 GS 很常见，尤其是在年轻人、女性和城市地区，尽管其患病率低于最近在英国进行的一项类似研究。不能排除 FODMAPs 部分导致了这些症状。
