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[HLA - B37和HLA - B27抗原会发生交叉反应吗?]

[Do HLA-B37 and HLA-B27 antigens cross react?].

作者信息

Májský A

出版信息

Vnitr Lek. 1989 Jan;35(1):50-1.

PMID:2784601
Abstract

Anti-HLA-B37 serum of Behringwerke gave a positive cytotoxic test with 18 of 24 samples of B37 negative B27 positive lymphocytes. With lymphocytes which had none of these antigens the reaction was always negative. The author discusses whether the results are evidence of the cross reactivity between antigens HLA-B37 and B27 or whether it is due to traces of anti-HLA-B27 antibodies in the above serum.

摘要

德国贝林厂生产的抗HLA - B37血清,对24份B37阴性B27阳性淋巴细胞样本中的18份进行细胞毒性试验呈阳性。对于不具备这些抗原的淋巴细胞,反应始终为阴性。作者探讨了这些结果是HLA - B37和B27抗原之间存在交叉反应的证据,还是归因于上述血清中存在微量抗HLA - B27抗体。

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