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运用基于理论的方法开发一项干预措施,以改善初级保健中老年人的合理联合用药情况。

Development of an intervention to improve appropriate polypharmacy in older people in primary care using a theory-based method.

作者信息

Cadogan Cathal A, Ryan Cristín, Francis Jill J, Gormley Gerard J, Passmore Peter, Kerse Ngaire, Hughes Carmel M

机构信息

School of Pharmacy, Royal College of Surgeons in Ireland, Dublin, Ireland.

School of Health Sciences, City University London, London, UK.

出版信息

BMC Health Serv Res. 2016 Nov 16;16(1):661. doi: 10.1186/s12913-016-1907-3.

Abstract

BACKGROUND

It is advocated that interventions to improve clinical practice should be developed using a systematic approach and intervention development methods should be reported. However, previous interventions aimed at ensuring that older people receive appropriate polypharmacy have lacked details on their development. This study formed part of a multiphase research project which aimed to develop an intervention to improve appropriate polypharmacy in older people in primary care.

METHODS

The target behaviours for the intervention were prescribing and dispensing of appropriate polypharmacy to older patients by general practitioners (GPs) and community pharmacists. Intervention development followed a systematic approach, including previous mapping of behaviour change techniques (BCTs) to key domains from the Theoretical Domains Framework that were perceived by GPs and pharmacists to influence the target behaviours. Draft interventions were developed to operationalise selected BCTs through team discussion. Selection of an intervention for feasibility testing was guided by a subset of the APEASE (Affordability, Practicability, Effectiveness/cost-effectiveness, Acceptability, Side-effects/safety, Equity) criteria.

RESULTS

Three draft interventions comprising selected BCTs were developed, targeting patients, pharmacists and GPs, respectively. Following assessment of each intervention using a subset of the APEASE criteria (affordability, practicability, acceptability), the GP-targeted intervention was selected for feasibility testing. This intervention will involve a demonstration of the behaviour and will be delivered as an online video. The video demonstrating how GPs can prescribe appropriate polypharmacy during a typical consultation with an older patient will also demonstrate salience of consequences (feedback emphasising the positive outcomes of performing the behaviour). Action plans and prompts/cues will be used as complementary intervention components. The intervention is designed to facilitate the prescribing of appropriate polypharmacy in routine practice.

CONCLUSION

A GP-targeted intervention to improve appropriate polypharmacy in older people has been developed using a systematic approach. Intervention content has been specified using an established taxonomy of BCTs and selected to maximise feasibility. The results of a future feasibility study will help to determine if the theory-based intervention requires further refinement before progressing to a larger scale randomised evaluation.

摘要

背景

提倡采用系统方法来制定旨在改善临床实践的干预措施,并应报告干预措施的开发方法。然而,以往旨在确保老年人合理用药的干预措施在其开发方面缺乏细节。本研究是一个多阶段研究项目的一部分,该项目旨在开发一种干预措施,以改善基层医疗中老年人的合理用药情况。

方法

该干预措施的目标行为是全科医生(GP)和社区药剂师为老年患者开具和调配合理的多种药物。干预措施的开发遵循系统方法,包括先前将行为改变技术(BCT)映射到全科医生和药剂师认为会影响目标行为的理论领域框架的关键领域。通过团队讨论制定了初步干预措施,以实施选定的BCT。根据APEA SE(可承受性、实用性、有效性/成本效益、可接受性、副作用/安全性、公平性)标准的一个子集来指导选择用于可行性测试的干预措施。

结果

制定了三项包含选定BCT的初步干预措施,分别针对患者、药剂师和全科医生。在使用APEA SE标准的一个子集(可承受性、实用性、可接受性)对每项干预措施进行评估后,选择了针对全科医生的干预措施进行可行性测试。该干预措施将包括行为示范,并将以在线视频的形式提供。展示全科医生在与老年患者的典型会诊中如何开具合理多种药物的视频还将展示后果的显著性(强调执行该行为的积极结果的反馈)。行动计划和提示/线索将用作补充干预组件。该干预措施旨在促进在常规实践中开具合理的多种药物。

结论

已采用系统方法开发了一种针对全科医生的干预措施,以改善老年人的合理用药情况。干预内容已使用既定的BCT分类法进行了明确,并进行了选择以最大化可行性。未来可行性研究的结果将有助于确定基于理论的干预措施在进行更大规模的随机评估之前是否需要进一步完善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/706f/5112618/e06870891abc/12913_2016_1907_Fig1_HTML.jpg

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