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双侧经椎间孔胸腰椎椎体间融合术治疗巨大中央型胸腰段交界区椎间盘突出症:一项前瞻性临床与影像学研究。

Bilateral transformational thoracolumbar interbody fusion for the treatment of giant central thoracolumbar junction disc herniation: A prospective clinical and radiological study.

作者信息

Wentao Wang, Kun Duan, Tuanjiang Liu, Minjie Ma, Yong Jiang, Baorong He, Qining Wu, Jijun Liu, Dingjun Hao

机构信息

Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, Shan'xi Province, China; Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University health science center, Nanguo Road No.76, Xi'an 710054, Shan'xi Province, China.

Department of General Surgery, The 417th Hospital, China National Nuclear Corporation (CNNC), Xi'an 710064, Shan'xi Province, China.

出版信息

J Orthop. 2015 Dec 10;13(4):461-466. doi: 10.1016/j.jor.2015.10.022. eCollection 2016 Dec.

Abstract

STUDY DESIGN

Clinical and radiological assessment of prospective single-center data.

BACKGROUND

The optimal treatment strategy for giant central thoracolumbar junction disc herniation (TLDH) remains controversial.

OBJECTIVE

This study aimed to report the clinical and radiological results of bilateral transformational thoracolumbar interbody fusion (bilateral TTIF) to treat giant central TLDH.

METHODS

Seventeen consecutive patients with giant central TLDH underwent bilateral TTIF from January 2014 to June 2014 and were followed for 9-15 months. Clinical and radiological data were prospectively examined, including operative time, blood loss, pre- and postoperative American Spinal Injury Association (ASIA) score for sensory and motor function, visual analog scale (VAS) and Oswestry Disability Index (ODI) scores, fusion rate, extent of decompression, rate of instrumentation failure, and complications.

RESULTS

The average time of surgery was 160 ± 37 min, and blood loss was 884 ± 197 ml. The ASIA sensory and motor scores improved from 72.76 ± 3.36 to 90.71 ± 2.54 and from 68.47 ± 4.7 to 88.0 ± 3.2, respectively. VAS for back pain and ODI decreased from 6.65 ± 1.93 to 2.23 ± 0.56 and from 42.82 ± 5.08 to 11.3 ± 2.3, respectively. Canal encroachment improved from 50.3 ± 6.6% to 2 ± 0.3% at the last follow-up. Surgery complications were seen in 5 patients (29%), who experienced intraoperative dural tear and cerebrospinal fluid leak. There were no other major complications at the last follow-up.

CONCLUSIONS

Bilateral TTIF produced satisfactory outcomes and may be one of the surgical treatments of choice for myelopathy due to giant central TLDH.

摘要

研究设计

对前瞻性单中心数据进行临床和影像学评估。

背景

巨大型胸腰段中央型椎间盘突出症(TLDH)的最佳治疗策略仍存在争议。

目的

本研究旨在报告双侧经椎间孔胸腰椎椎间融合术(双侧TTIF)治疗巨大型中央型TLDH的临床和影像学结果。

方法

2014年1月至2014年6月,17例连续的巨大型中央型TLDH患者接受了双侧TTIF手术,并进行了9至15个月的随访。对临床和影像学数据进行前瞻性检查,包括手术时间、失血量、术前和术后美国脊髓损伤协会(ASIA)感觉和运动功能评分、视觉模拟量表(VAS)和Oswestry功能障碍指数(ODI)评分、融合率、减压程度、内固定失败率和并发症。

结果

平均手术时间为160±37分钟,失血量为884±197毫升。ASIA感觉和运动评分分别从72.76±3.36提高到90.71±2.54,从68.47±4.7提高到88.0±3.2。背痛VAS和ODI分别从6.65±1.93降至2.23±0.56,从42.82±5.08降至11.3±2.3。末次随访时椎管侵占率从50.3±6.6%改善至2±0.3%。5例患者(29%)出现手术并发症,术中发生硬脊膜撕裂和脑脊液漏。末次随访时无其他严重并发症。

结论

双侧TTIF取得了满意的结果,可能是巨大型中央型TLDH所致脊髓病的手术治疗选择之一。

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